PURPOSE To conduct a comparative study of static accommodative function between individuals with normal vision (n = 10) and patients with congenital nystagmus (n = 12). METHODS The component contribution to monocular steady-state accommodation (slope of the accommodative stimulus/response function, accommodative controller gain, tonic accommodation, and depth-of-focus) was assessed subjective...

Congenital nystagmus is a pathologic oculomotor state appearing at about three to four months of age. The precise diagnosis requires detailed clinical examination and electrophysiological findings. This case report presents two male patients with congenital nystagmus examined longitudinally from the age of six months until 17-18 years of age. Clinical and electrophysiological protocols were det...

Visual acuity in congenital nystagmus is primarily related to the duration of the foveation periods, during which the image of the target is placed on the fovea area and the eye velocity is low. This is true only if the subject is still able to place the target image on the centralmost fovea during the foveation period. In presence of a high variability of the foveation position the target imag...

We applied new methods for canine eye-movement recording to the study of achiasmatic mutant Belgian Sheepdogs, documenting their nystagmus waveforms and comparing them to humans with either congenital nystagmus (CN) alone or in conjunction with achiasma. A sling apparatus with head restraints and infrared reflection with either earth- or head-mounted sensors were used. Data were digitized for l...

BACKGROUND Pendular nystagmus commonly occurs in congenital and acquired disorders of myelin. OBJECTIVE To characterize the nystagmus in 3 siblings with an infantile form of an autosomal recessive peroxisomal assembly disorder causing leukodystrophy. DESIGN We examined visual function and measured eye movements using infrared oculography. We noted changes in eye speed and frequency before a...

Vestibular and optokinetic responses were recorded in three albino subjects with congenital nystagmus. Although an ice-water caloric stimulus did not elicit nystagmus, all patients showed a response to rotational stimuli containing high frequency components. Vestibular responses to a constant velocity rotation decremented with abnormally short time constants of 1-2 sec (normal 15-20 sec). For s...

In an unselected series of 644 cases of multiple sclerosis, 25 cases with acquired pendular nystagmus were found. Ten additional cases of pendular nystagmus in multiple sclerosis were investigated, and four cases from the literature are analysed. Acquired pendular nystagmus is purely sinusoidal in form, ceases with eye closure, is accompanied by oscillopsia, often monocular and vertical in dire...