Background The Mendelian Susceptibility to Mycobacterial Diseases (MSMD) is a rare congenital syndrome that confers a predisposition to recurrent infections by mycobacteria. All genetic defects that lead to MSMD produce changes at IL-12/23-IFN-g axis. We aimed to evaluate the IL-12/ 23-IFN-g axis in adult patients with recurrent mycobacterial infections in order to identify possible MSMD patients.

TORCH, includes Toxoplasmosis, Other (syphilis, varicella-zoster, parvovirus B19, Hepatitis B), Rubella, Cytomegalovirus (CMV), and Herpes infections are some of the most common infections associated with congenital anomalies. Most of the TORCH infections have serious fetal consequences and there has no impact on fetal outcome. In the present article, we wanted to discuss about the causative ag...

The increase in the popularity of breast feeding and utilization of child care arrangements are having a major effect on the epidemiology of cytomegalovirus infections. The impact is greater for women of upper socioeconomic background who send their toddlers to day-care centers and for day-care workers. If primary cytomegalovirus infections occur during pregnancy it is logical to anticipate mor...

Preconception and prenatal monitoring evaluate the condition of mother's underlying disease possible complications during pregnancy. Before conception, patients with diabetes should be informed that suboptimal glycoregulation is associated reduced fertility pregnancy losses. The task perinatologist in pregnancies affected by mellitus to prevent disease, such as hypoglycemic crises. Another impo...

Neutropenia is common in the practice of both primary care physicians and sub-speciality. Congenital neutropenia are rare diseases; they can be isolated independent diseases accompany a number other inborn errors immunity. The clinical course range from asymptomatic patients with mild to life-threatening infections cases severe neutropenia. Treatment congenital remains discutable this day. most...

Paediatric bilateral multiple trigger fingers are extremely rare. The underlying etiopathogenesis and hence the surgical principles of management of trigger finger in children are different from those of pediatric trigger thumb and adult trigger finger. In this paper, we report the case of a 5 year old girl with congenital trigger digits involving the middle, ring and little fingers of both han...

surgery has led to a reduction in febrile morbidity rates (Qvistad et al. 1983; Crowley et al. 2001). If screening is not practical, many clinics and practitioners routinely treat all women receiving surgical abortion for chlamydia presumptively and, in high prevalence areas, would treat for gonorrhea as well. Intrauterine infection may be the result of hematogenous or ascending infection. For ...

Congenital Zika virus infection can cause microcephaly and other severe fetal neurological anomalies (1). To inform microcephaly surveillance efforts and assess ascertainment sources, the New York State Department of Health and the New York City Department of Health and Mental Hygiene sought to determine the prevalence of microcephaly in New York during 2013-2015, before known importation of Zi...