The aim of this investigation was to prepare, characterize and optimize the aceclofenac proniosomes using central composite design and carry out stability studies. Three independent variables selected were molar ratio of drug to lipid (X1), surfactant loading (X2) and volume of hydration (X3). Based on central composite design, 16 batches of proniosomes were prepared by slurry method and evalua...

this study investigates natural frequency analysis of an fg composite rectangular plate partially contacting with a bounded fluid. the material properties are assumed to be varying continuously through the thickness direction according to a simple power law distribution in terms of volume fraction of material constituents. wet dynamic transverse displacements of the plate are approximated by a ...

The optimization of aerospace structures is a very complex problem, owing to the hundreds of design variables a multidisciplinary optimization may contain, so that multilevel optimization is required. This paper presents recent developments to the optimization software VICONOPT MLO, a multilevel optimization interface between the analysis and design software packages VICONOPT and MSC/NASTRAN. T...

A numerical study on toughening laminated composite materials against delamination by initiating multiple interlaminar cracks is presented. Different configurations of interface and weakening patches, that modify the properties at selected locations, are investigated as a way to trigger delaminations. Both patches can be configured toughen material The initiation delaminations increase in tough...

Self-healing resin systems have been discussed for over a decade and four different technologies had been proposed. However, little work on their application as composite matrices has been published although this was one of the stated aims of the earliest work in the field. This paper reports on the optimization of a solid-state self-healing resin system and its subsequent use as a matrix for h...

The buckling and postbuckling behaviors of a composite beam with single delamination are investigated. A three-dimensional finite element model using the commercial code ANSYS is employed for this purpose. The finite elements analyses have been performed using a linear buckling model based on the solution of the eigenvalues problem, and a non-linear one based on an incremental-iterative method....