Aim This study was aimed to evaluating the efficacy of levofloxacin based sequential therapy vs clarithromycin based sequential therapy in h.pylori (HP) eradication. Background Several therapeutic regimen were investigated to treat HP infection. Sequential therapy is an alternative to classic triple therapy. Methods In this randomized clinical trial, 200 HP infected patients randomly divide...

BACKGROUND The combination of ribavirin (RBV) and pegylated interferon (PEG-IFN) is effective in the treatment of chronic hepatitis C infection. Reducing the frequency of RBV intake from twice to once a day will improve compliance and opens up the opportunity to combine RBV with new and more specific direct-acting agents in one pill. Therefore, the purpose of this study was to evaluate the phar...

INTRODUCTION Compliance with antidiabetic therapy has the potential to impact on the risk for complications by an effect on glycemic control. Fixed-dose combinations (FDCs) offer a simplified dosing regimen that may improve patient compliance. We undertook a retrospective database analysis to understand the real-world association between FDCs, treatment practices, glycated hemoglobin (HbA(1c)) ...

although successful iron chelation with deferiprone is associated with significant complications, patient’s compliance with medication regimens is of a high priority. the present study did evaluate the complications and compliance of domestically-manufactured deferiprone combined with desferrioxamine for iron chelation therapy. a total of 32 major beta thalassemic patients with cardiomyopathy w...

Hypertension is common in the elderly. While it is possible to reduce blood pressure in this age group, the value of such treatment in terms of reduced mortality and morbidity is unknown. The effects of a prescribed regimen depends inter alia on compliance. Therefore, this variable must be taken into account in assessing drug treatment in the elderly hypertensive. In general, the elderly comply...

asthma affects an estimated 300 million people worldwide. poor compliance with the prescribed medication leads to increased mortality and morbidity. various determinants of compliance have been described. the purpose of this study was to determine factors that can influence patients' compliance with prescribed metered dose inhaler drugs. 179 patients with diagnosis of asthma were selected from ...

The purpose of this study was to compare an experimental regimen of atovaquone plus proguanil with the standard regimen of quinine plus tetracycline for the treatment of uncomplicated falciparum malaria. The study was designed as an open, randomized study of men presenting with symptoms of uncomplicated malaria and thick-smear slide confirmation of parasitemia (1000-100,000 ring forms/microL). ...

conclusions if such a regimen is approved, it would be a breakthrough in the treatment of hcv in subjects with hemoglobinopathy. more prospective, randomized control trial studies are needed to investigate the efficacy and safety profile of such a regimen. case presentation we described a 16- year-old male patient with sickle-thalassemia who was infected with a hcv. treatment was started with s...

background: low compliance with drugs regimens in diabetic patients is one of the greatest challenges in the treatment of diabetes. the aim of this study was to evaluate compliance with medical orders in diabetic patients referred to the endocrinology clinic of afzalipour hospital, kerman, iran. methods: in this cross sectional study 345 of the 3000 patients, who referred to the endocrinology c...