Inspired by the recent developments in modeling and analysis of reaction networks, we provide a geometric formulation of the reversible reaction networks under the influence of diffusion. Using the graph knowledge of the underlying reaction network, the obtained reaction-diffusion system is a distributed-parameter port-Hamiltonian system on a compact spatial domain. Motivated by the need for co...

In vivo compartmental analysis of leukocytes in mouse lungs 1 2 Brijesh V Patel, Kate C Tatham, Michael R Wilson, Kieran P O’Dea, and Masao Takata 3 4 1 Section of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial 5 College London, Chelsea and Westminster Hospital, London, United Kingdom. 6 7 Running Head: Compartmental analysis of mouse lungs 8 9 Address corresponde...

UNLABELLED Assessing cellular proliferation provides a direct method to measure the in vivo growth of cancer. We evaluated the application of a model of 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) kinetics described in a companion report to the analysis of FLT PET image data in lung cancer patients. Compartmental model analysis was performed to estimate the overall flux constants (K(FLT)) for...

The fluorescence and polarization anisotropy decays of perylene in viscous solvents are investigated at several temperatures between -20 and 35 OC by using the technique of multifrequency phase and modulation fluorometry. The anisotropy decay data are globally analyzed over all temperatures studied and fit directly to physical quantities by using a compartmental model. We present a generalized ...

The lung has a unique structure consisting of three functionally different compartments (alveolar, interstitial, and vascular) situated in an extreme proximity. Current methods to localize lung leukocytes using bronchoalveolar lavage and/or lung perfusion have significant limitations for determination of location and phenotype of leukocytes. Here we present a novel method using in vivo antibody...

This study was conducted to examine the statistical influence of brain size on cortical, subcortical, and cerebellar compartmental volumes. This brain size influence was especially studied to delineate interactions with Sex and Age. Here, we studied 856 healthy subjects of which 533 are classified as young and 323 as old. Using an automated segmentation procedure cortical (gray and white matter...