We have investigated the relationship between chronic lymphocytic leukemia (CLL), hairy cell leukemia (HCL), and different normal B cell subsets: Mrbc+, T1+ and slgM+ tonsil cells; germinal center; mantle zone; and peripheral blood B lymphocytes. Both malignant and normal cells were incubated in vitro with the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate (TPA) for 72 hours and the morpho...

the down-flow hanging sponge (dhs) reactor, which was developed for post-treatment of effluent from up-flow anaerobic sludge blanket (uasb) process treating sewage, uses polyurethane sponge as media to retain biomass. wastewater is trickled from the top of the reactor and purified by microorganisms retained both inside and outside of the sponge media as the wastewater flows vertically down thr...

Nonunion is a common complication in open fractures and other severe bone injuries. Recombinant human bone morphogenetic protein-2 (rhBMP-2) delivered on a collagen sponge enhances healing of fractures. However, the burst release of rhBMP-2 necessitates supra-physiological doses of rhBMP-2 to achieve a robust osteogenic effect, which introduces risk of ectopic bone formation and severe inflamma...

sponge iron (dri) due to the high surface area, often shows a high tendency to re-oxidation and at some cases spontaneous combustion (autoignition). in this work, re-oxidation behavior and autoignition of sponge iron, produced from different types of iron ore has been investigated. isothermal and non-isothermal re-oxidation experiments were carried out on each type of dri and their autoignition...

OBJECTIVE To evaluate race differences in tissue plasminogen activator (tPA) refusal among eligible patients with acute ischemic stroke (AIS) in Chicago. METHODS Using the Get With The Guidelines-Stroke registry data from 15 primary stroke centers between January 2013 and June 2015, we performed a retrospective analysis of patients with AIS presenting to the emergency department within 4.5 ho...

By new advancements in vehicle manufacturing vehicle quality evaluation and assurance has become a more critical issue. In present work, the vibration transfer path analysis and vibration path ranking of a car interior has been performed. The method is similar to classical multilevel TPA methods but has distinct differences. The method is named VIVS which stands for Vehicle Interior Vibratio...

BACKGROUND Tissue plasminogen activator (tPA) is used emergently to dissolve thrombi in the treatment of fulminant pulmonary embolism. Currently, there is a relative contraindication to tPA in the setting of traumatic or prolonged cardiopulmonary resuscitation > 10 minutes because of the risk of massive hemorrhage. METHODS Our single-center, retrospective study investigated patients experienc...