نتایج جستجو برای: combined treatment

تعداد نتایج: 1704870  

Journal: :Antimicrobial agents and chemotherapy 1976
R E Scott H G Robson

Rats made neutropenic with cyclophosphamide were infected intraperitoneally with Pseudomonas aeruginosa. The challenge organism was killed synergistically in vitro by the combination of gentamicin and carbenicillin. Untreated neutropenic rats infected with 3 x 10(6)Pseudomonas died between days 2 and 7, and the overall mortality was 70%. Groups of infected neutropenic rats were treated intramus...

Journal: :Annals of the rheumatic diseases 2007
Lilian H D van Tuyl Anne Marie C Plass Willem F Lems Alexandre E Voskuyl Ben A C Dijkmans Maarten Boers

BACKGROUND The Combinatietherapie Bij Reumatoide Artritis (COBRA) trial has proved that combination therapy with prednisolone, methotrexate and sulphasalazine is superior to sulphasalazine monotherapy in suppressing disease activity and radiological progression of early rheumatoid arthritis (RA). In addition, 5 years of follow-up proved that COBRA therapy results in sustained reduction of the r...

Journal: :Pain medicine 2012
Lakshmi Vas Renuka Pai

Bilateral complex regional pain syndrome (CRPS) appears to be unusual [1–5]. We report details of bilateral CRPS diagnosed by International Association for Study of Pain (IASP) criteria in five patients who presented with florid symptoms (more prominent in one extremity) that persisted despite physical therapy (PT) and medications (Figure 1). They were effectively treated with a novel multimoda...

Journal: :Anticancer research 2010
Kazuteru Ryu Hiroaki Murata Kazutaka Koto Naoyuki Horie Takaaki Matsui Yasunori Nishigaki Tomoya Sakabe Hideyuki Takeshita Megumi Itoi Shinya Kimura Eishi Ashihara Taira Maekawa Shinji Fushiki Toshikazu Kubo

UNLABELLED Antitumour effects of third-generation bisphosphonates (BPs), such as zoledronic acid (ZOL), and the combined effects of ZOL with other anticancer agents against osteosarcoma cells have been reported previously. The aim of this study was to identify further combined antitumour effects using BPs and radiation in osteosarcoma cell lines. MATERIALS AND METHODS Cell proliferation, cell...

2014
Alexandra Kutzelnigg Martin Kopeinig Chih-Ken Chen Ágnes Fábián María Gloria Pujol-Luna Young-chul Shin Tamás Treuer Yulia D’yachkova Claudia Deix Siegfried Kasper Dagmar Doby

Compliance is a key factor in the maintenance treatment of bipolar disorder. This noninterventional study was conducted to explore factors associated with higher levels of compliance in bipolar patients, all treated in routine clinical settings. Bipolar outpatients (Clinical Global Impression of Severity score ≤3) who had been stabilized with olanzapine mono- or combination therapy for ≥4 weeks...

Journal: :American journal of therapeutics 2010
Anil Pareek Harsha Salkar Pradeep Mulay Shubha Desai Nitin Chandurkar Neelam Redkar

As there is a strong, positive, and continuous correlation between blood pressure and risk of cardiovascular diseases; improved control of blood pressure is necessary to produce maximum reduction in clinical cardiovascular endpoints. The primary objective was to demonstrate that atenolol/amlodipine combination therapy is superior to atenolol monotherapy with respect to mean fall in systolic blo...

Journal: :American journal of respiratory and critical care medicine 1996
R D Moore C P Chaulk R Griffiths S Cavalcante R E Chaisson

Decision analysis was used to compare three alternative strategies for a 6-mo course of treatment for tuberculosis: directly observed drug therapy (DOT), self-administered fixed-dose combination drug therapy, and self-administered conventional individual drug therapy. Estimates of effectiveness were obtained from the published literature. Estimates of costs were obtained from the literature and...

2014
Satoshi Takakuwa Yoko Kina

The initial treatment of childhood-onset Graves' disease is based on the result of clinical trials of adult-onset disease. The major adverse events associated with methimazole, the only medication approved for childhood-onset disease in Japan, are considered to depend on the dose, and the risk of adverse events is increased in patients requiring higher doses for initial treatment. The serum lev...

Journal: :The oncologist 2004
Mary Koshy Natia Esiashvilli Jerome C Landry Charles R Thomas Richard H Matthews

The overall success rate nationally in treating esophageal carcinomas remains poor, with over 90% of patients succumbing to the disease. In part I of this two-part series, we explored epidemiology, presentation and progression, work-up, and surgical approaches. In part II, we explore the promising suggestions of integrating chemotherapy and radiation therapy into the multimodal management of es...

2017
Raya Saab Zeina Merabi Miguel R. Abboud Samar Muwakkit Peter Noun Gladys Gemayel Elie Bechara Hassan Khalifeh Roula Farah Nabil Kabbara Tarek El-Khoury Rasha Al-Yousef Rachid Haidar Said Saghieh Toufic Eid Samir Akel Nabil Khoury Layal Bayram Matthew J. Krasin Sima Jeha Hassan El-Solh

BACKGROUND Children with malignant bone tumors have average 5-year survival rates of 60% to 70% with current multimodality therapy. Local control modalities aimed at preserving function greatly influence the quality of life of long-term survivors. In developing countries, the limited availability of multidisciplinary care and limited expertise in specialized surgery and pediatric radiation ther...

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