نتایج جستجو برای: column base
تعداد نتایج: 328858 فیلتر نتایج به سال:
AbstractExposed column base plate (ECBP) connections are commonly used in steel moment resisting frames. Current approaches for their design well-established from a mechanistic standpoint. Howe...
The kinetic performance of a bare silica and C18 phase prepared from the same sub-2μm and 3.5μm base materials were compared in the HILIC and RP mode using both charged and neutral solutes. The HILIC column was characterised using the neutral solute 5-hydroxymethyluridine, the weak base cytosine, and the strong base nortriptyline, the latter having sufficient retention also in the RP mode to al...
Proof. We induct on d. Exercise 1 proved the base case d = 1. Consider d ≥ 2 and a d-disjunct matrix M with t = t(d,N) rows and N columns. Let N(w) denote the number of columns of M with weight w. (The weight of a column is the number of 1s in it.) A row i ∈ [t] is said to be private for a column j if j is the only column in the matrix having a 1 on row i. If column Mj has weight at most d, the...
Analytical methods were developed for the identification of major degradation products of Ketoconazole, an antifungal agent. The stressed degradation of Ketoconazole drug substance was performed under acid, base, thermal, photo and oxidative stress conditions. The major degradation was observed under acid, base and oxidative stress conditions. The degradation study was performed on Inertsil ODS...
μABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA
We present the results of microsecond molecular dynamics simulations carried out by the ABC group of laboratories on a set of B-DNA oligomers containing the 136 distinct tetranucleotide base sequences. We demonstrate that the resulting trajectories have extensively sampled the conformational space accessible to B-DNA at room temperature. We confirm that base sequence effects depend strongly not...
We present a generic model for DNA at the base-pair level. We use a variant of the Gay-Berne potential to represent the stacking energy between the neighboring base pairs. The sugar-phosphate backbones are taken into account by semirigid harmonic springs with a nonzero spring length. The competition between these two interactions and the introduction of a simple geometrical constraint lead to a...
Chromatography is commonly used as a purification method for synthetic oligodeoxyribonucleotides (1). Anion exchange chromatography on Mono Q column (Pharmacia), under denaturing conditions and using non-organic buffers, gives adequate purity for sequences up to 50 bases long (2). The eluting NaCl concentration primarily depends on the oligonucleotide length. However, base composition and seque...
For this example, 19/40=47.5% of the columns have a carry of 1. Holte shows that if the binary digits are chosen at random, uniformly, in the limit 50% of all the carries are zero. This holds no matter what the base. More generally, if one adds n integers (base b) that are produced by choosing their digits uniformly at random in {0, 1, . . . , b− 1}, the sequence of carries κ0 = 0, κ1, κ2, . . ...
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