This study was conducted to investigate the clinicopathological features of synchronous cancers and treatment options according to their locations.Records of 8368 patients with colorectal cancer treated at our center between July 2003 and December 2010 were analyzed retrospectively. All synchronous colorectal cancer patients who underwent surgical treatment were included.Synchronous cancers wer...

Background Right colectomy is the surgical treatment for malignant pathologies involving the intestinal tract between the ileocecal Bahuino valve and the colic hepatic flexure. Laparoscopic resection must respect the same oncological criteria as the open approach including: ‘’no-touch isolation technique’’, isolation and ligation of the vascular pedicles at the origin, oncological lymphadenecto...

BACKGROUND & AIMS Hirschsprung disease (HSCR) is caused by failure of cells derived from the neural crest (NC) to colonize the distal bowel in early embryogenesis, resulting in absence of the enteric nervous system (ENS) and failure of intestinal transit postnatally. Treatment is by distal bowel resection, but neural cell replacement may be an alternative. We tested whether aneuronal (aganglion...

A 52-year-old man underwent laparoscopic resection of the sigmoid colon for recurrent sigmoid diverticulitis in another hospital. Owing to anastomotic leakage and anastomotic stenosis, several dilatations were carried out. Two months later open resection of the anastomotic stenosis was done. Three months after that, he presented to our hospital because of symptoms of subileus due to a recurrent...

Intussusception is a rare cause of intestinal obstruction in adult patients, but is common in children. In fact, it accounts for an estimated 1% of all cases of bowel obstruction in adults, although adult intussusception of the large intestine is rare. Sigmoidorectal intussusception, however, is a rare variety with few cases reported in the literature. A mucinous adenocarcinoma, a subtype of ad...

A 77-year-old man with a 3-cm slightly elevated, nongranular type, laterally spreading tumor (LST-NG 0-IIa) of the sigmoid colon was referred to our institute for endoscopic resection (●" Fig.1). Piecemeal underwater endoscopic mucosal resection (UEMR) was carried out with a high definition narrow band endoscope (CF-H190L; Olympus Europa SE, Hamburg, Germany). After UEMR, the margins were ablat...

BACKGROUND/AIMS Increasing negative lymph node count has been reported to be associated with better outcomes in patients with colon cancer. The present study aimed to clarify the clinical significance of the lymph node ratio (LNR) and location of lymph node metastasis (LNM) in patients with stage III right colon cancer. METHODS We enrolled 820 patients who had undergone curative resection due...

To elucidate the role of luminal nutrients and glucagon-like peptide-2 (GLP-2) in intestinal adaptation, rats were subjected to 70% midjejunoileal resection or ileal transection and were maintained with total parenteral nutrition (TPN) or oral feeding. TPN rats showed small bowel mucosal hyperplasia at 8 h through 7 days after resection, demonstrating that exogenous luminal nutrients are not es...