Rhabdoid tumor of the kidney is a rare and aggressive childhood cancer (1). Although the infant kidney is the most common site of rhabdoid tumors, these tumors occasionally occur at other sites and in older children and adults (2,3). Less than 25% of infants and young children with rhabdoid tumor of the kidney survive (4,5). Rhabdoid tumor is defined histologically by large cells, which may res...

Note Primary CNS tumors constitute a spectrum of pathological entities each with a distinct natural history that reflects the sequential accumulation of genetic lesions and the deregulation of growth-factor signalling pathways during neoplastic transformation. For simplicity, CNS tumors may be classified as GLIOMAS or NONGLIOMAS (see Table 1 which provides a summary of 2007 World Health Organiz...

BACKGROUND Years of potential life lost (YPLL) complement incidence and survival rates by measuring how much a patient's life is likely to be shortened by his or her cancer. In this study, we examine the impact of death due to brain and other central nervous system (CNS) tumors compared to other common cancers in adults by investigating the YPLL of adults in the United States. METHODS Mortali...

Abstract Although immune checkpoint inhibitors (ICI) have become a useful tool in the management of central nervous system (CNS) metastases, only subset patients experience durable clinical responses and prognosis continues to remain poor. In particular, role ICI for CNS metastases from breast cancer has also not been adequately explored. CDK4/6 inhibition shown sensitize extracranial tumors IC...

Central nervous system (CNS) hemangioblastoma is the most common manifestation of von Hippel-Lindau (VHL) disease. It is found in 70-80% of VHL patients. Hemangioblastoma is a rare form of benign vascular tumor of the CNS, accounting for 2.0% of CNS tumors. It can occur sporadically or as a familial syndrome. CNS hemangioblastomas are typically located in the posterior fossa and the spinal cord...

Abstract BACKGROUND Despite advances in cancer diagnosis and clinical care, survival for many primary brain other central nervous system (CNS) tumors remain poor. This study performs a comprehensive analysis on these tumors. METHODS Survival differences were determined utilizing the National Program of Cancer Registries Analytic file all CNS Overall 5 most common histopathologies within specifi...

BACKGROUND Multimodal treatment approaches for children with tumors of the central nervous system (CNS) have markedly contributed to improved survival. Before 1970, the survival rate among children with medulloblastoma, the most common malignant CNS tumor in children, was about 20%. At present, in contrast, cure can be achieved in more than 75% of children with a favorable constellation of risk...

Von Hippel-Lindau (VHL) syndrome is a rare neoplastic disorder characterized by central nervous system (CNS) and visceral tumors. We here present (68)Ga-labelled [1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid]-1-Nal3-Octreotide positron emission tomography computed tomography findings in a 52 year old female with VHL syndrome, demonstrating both CNS and visceral tumors.