Clostridium difficile associated disease is a well recognized nosocomial infection evolving as a severediarrheal illness, associated with significantly higher rates of morbidity and mortality in critically ill patients. The incidence of Clostridium difficile infection is higher and its impact is more severe in trauma patients when compared with general inpatient population. There are several po...

bacteriocins are proteinaceous antibacterial compounds that exhibit bactericidal activity against species closely related to the producer strain. the aim of this research was to investigate the production of bacteriocin by bacillus spp. isolated from intestinal bacterial flora of the caspian frisian roach (rutilus frisii kutum). a bacteriocin produced by the bacterium bacillus cereus strain rf ...

Clostridium botulinum is a spore-forming bacterium that can produce a very powerful neurotoxin that causes botulism. In this study, we have investigated the Fur transcription regulators in Clostridium botulinum and Fur-regulated genes in Clostridium botulinum A ATCC 3502. We found that gene loss may be the main cause leading to the different numbers of Fur transcription regulators in different ...

Evidence has accumulated indicating that the clostridia ferment glucose by means of a system similar to the Embden-Meyerhof-Parnas (EMP) pathway (Elsden, 1952). In the case of Clostridium perfringens, for instance, most of the enzymes of the EMP pathway have been demonstrated in cell free extracts (Bard and Gunsalus, 1950; Shankar and Bard, 1955). Further evidence for the operation of the EMP p...

Reactive arthritis is a rare complication of Clostridium difficile enterocolitis, especially in children. We review the 6 pediatric cases published in the English and non-English literature and discuss their clinical presentation, outcome, treatment, and pathophysiology. We also report the seventh case of Clostridium difficile reactive arthritis in a 6-year-old boy who was treated with amoxicil...

The concentration and viability of spores produced by four different strains of Clostridium chauvoei (C. feseri) grown in a modified medium for 18 days are described. The medium yielded enough viable spores for experimental work.

Clostridium strains from six phylogenetic groups, C. botulinum groups I to IV, C. baratii, and C. butyricum, display the capacity to produce botulinum neurotoxin. Here, we present the genome sequence of a C. butyricum isolate, the neurotoxigenic strain 5521, which encodes the type E botulinum neurotoxin.

Background Clostridium difficile is currently the most frequent cause of nosocomial diarrhea but also cause of disease in the community, antibiotic therapy and hospitalizations related; advanced age (over 60 years), malignancies, chronic kidney disease are also risk factors for infection with Clostridium difficile. The incidence of Clostridium difficile increases all over the world. The complic...

introduction: clostridium difficile is the etiologic agent of several infections such as pseudomembranous colitis in human. these diseases are frequently associated with antibiotic useage but many infections with this organisms are seen without antibiotic administration. in addition it is believed that clostridium difficile is one of the most important bacteria involved in acquired hospital inf...

clostridial myositis, considered to be rare in pet animals, is an acutely fatal toxaemic condition. some species of clostridia are responsible for necrotic myositis. a 2-year-old male german shepherd dog was admitted with non-weight bearing lameness and massive swelling of the left hind limb. clostridium perfringens type a with alpha toxin was diagnosed as a pathogenic agent. based on the histo...