In this paper, we propose a probabilistic modeling clonal selection algorithm which combines the clonal selection algorithm (CSA) and the probabilistic modeling (PM) for traveling salesman problem (TSP). The clonal selection algorithm is employed by the natural immune system to define the basic features of an immune response to an antigenic stimulus, can initialize antibodies and maintain the p...

In this short review we report the basic notions needed for understanding the population genetics of clonal diploids. We focus on the consequences of clonality on the distribution of genetic diversity within individuals, between individuals and between populations. We then summarise how to detect clonality in mainly sexual populations, conversely, how to detect sexuality in mainly clonal popula...

Artificial immune systems are a kind of new computational intelligence methods which draw inspiration from the human immune system. Most immune system inspired optimization algorithms are based on the applications of clonal selection and hypermutation, and known as clonal selection algorithms. These clonal selection algorithms simulate the immune response process based on principles of Darwinia...

Florida ziziphus Ziziphus celata is a self-incompatible clonal shrub comprising fewer than a dozen remnant, uniclonal populations in south-central Florida, USA. We model the population viability of this highly endangered species based on 9 yr of data from 2 populations. The matrix projection model is based on hypothetically independent ‘plants’ defined as clumps of ramets within a 25 cm radius....

Clonal diversity in cancer has been proposed as a mechanism underlying patientto-patient variability in therapeutic response, as well as the variability in the likelihood of relapse and the time to relapse of acute myeloid leukemia (AML) as well as other cancers. As a neoplasm develops it often continues to mutate, diversifying into differing clonal populations. Darwinian evolutionary pressures...

Estimating the rate of clonal reproduction in natural population of diploid organisms is recognised as being problematic and even the detection of strictly clonal populations is often controversial. One well-acknowledged signature of clonal reproduction is the generation of non-random associations between loci. Linkage disequilibrium (LD) is thus often used for estimating the amount of clonal r...

Ochrobactrum intermedium is considered as an emerging human environmental opportunistic pathogen with mild virulence. The distribution of isolates and sequences described in literature and databases showed frequent association with human beings and polluted environments. As population structures are related to bacterial lifestyles, we investigated by multi-locus approach the genetic structure o...