OBJECTIVE Frontotemporal lobar degeneration (FTLD) is characterized by impairments in social, behavioral, and/or language function, but postmortem studies indicate that multiple neuropathological entities lead to FTLD. This study assessed whether specific clinical features predict the underlying pathology. METHODS A clinicopathological correlation was performed on 90 consecutive patients with...

The patient, a 48-year-old black man, was first admitted to the hospital in late February 1993 because of fatigue, polyuria, polydipsia, and nocturia. To lose weight, he had been on a liquid diet and vitamins since November 1992 and had lost about 4.5 kg. He had remained active, working as an automobile mechanic. For several weeks before admission, he had been tired and weak and had noticed pol...

Prostatic atrophy is a benign lesion that may mimic adenocarcinoma histologically and on imaging. It is more frequent in the peripheral zone and has gained importance with the increasing use of needle biopsies. Diffuse atrophy occurs secondarily to radiotherapy and/or endocrine therapy. Inflammation and/or chronic local ischemia may cause focal atrophy with an increasing frequency in age. Atrop...

A 23-year-old man was seen in the clinic because of progressive weakness and paresthesias. He had been well until six months earlier, when he began to have difficulty climbing a flight of stairs quickly and noted intermittent tingling of the soles of his feet and toes. Two months later, he had increasing weakness in his legs, pain in the lower back, stiffness of the hands, and intermittent numb...

A one-year-old girl (resident of Bhatinda, Punjab) was first admitted at PGIMER under pediatric hematology-oncology at the advanced pediatric center on 05.10.2011 with complaints of fever and progressive abdominal distension for 1 and a half months. Fever was intermittent, associated with occasional vomiting and documented up to101°F. Vomiting was nonbilious and nonprojectile. She also had prog...

INTRODUCTION Clinicopathological correlation studies of cases admitted as meningococcal disease are scarce, although they can serve to elucidate clinically obscure cases. METHODS A descriptive approach was used to analyze 42 necropsies following clinical diagnosis of meningococcal disease, verifying the agreement between histopathological and clinical findings evaluated according to three cli...

OBJECTIVE To classify all renal biopsies of lupus nephritis patients presenting in the last 10 years, according to the modified World Health Organization (WHO) classification using the facilities of light, fluorescent, and electron microscopy. To assess the activity and chronicity indices of renal biopsies according to the National Institute of Health protocol, and to correlate the histological...

Since the original description of glial neoplasms consisting of cells with oligodendroglial morphology [1] many papers have addressed the clinical behavior of this tumor. While their name was derived from a characteristic appearance in silver stains as tumors composed of glial cells with few and short processes, the hallmark of oligodendrogliomas as shown in hematoxylin and eosin stains became ...

Background: Esthesioneuroblastoma is a rare tumour accounting for only 3% of all intranasal tumors. Its proximity with important structures and aggressive behavior presents a diagnostic and therapeutic challenge. CT, MRI and histopathology forms the basic pillars of management. Methods: A prospective study was conducted between Feb 1998 to Feb 2004 in the Department of ENT, JNMC, AMU Aligarh. A...

The clinicopathological characteristics of small gliomas were investigated in nine patients with gliomas less than 2 cm in diameter. The tumor histology and proliferative activity were also examined. Three tumors occurred in the white matter and six at the corticomedullary junction. Histological diagnosis, Daumas-Duport's grading, bromodeoxyuridine labeling index, and proliferating cell nuclear...