نتایج جستجو برای: clinical studies

تعداد نتایج: 2383309  

2010
Gian Carlos Navarro-Chumbes Silvia Margarita Montano-Torres Alberto Díaz-Vásquez Joseph Raymond Zunt

In Peru, despite a strong clinical research infrastructure in Lima, and Masters degree programs in epidemiology at three universities, few neurologists participate in clinical research. It was our objective to identify perceived needs and opportunities for increasing clinical research capacity and training opportunities for Peruvian neurologists. We conducted a descriptive, cross-sectional surv...

2012
Marianne Pitkäjärvi Elina Eriksson Kaisu Pitkälä

Background. Globalization within higher education leads to an increase in cultural and linguistic diversity in student populations. The purpose of this study was to explore culturally diverse health care students' experiences in clinical environment in Finland, and to compare them with those of native Finnish students' participating in the same program. Method. A cross-sectional survey was perf...

2016
Sebastian Heinzel Benjamin Roeben Yoav Ben-Shlomo Stefanie Lerche Guido Alves Paolo Barone Stefanie Behnke Henk W. Berendse Bastiaan R. Bloem David Burn Richard Dodel Donald G. Grosset Michele Hu Meike Kasten Rejko Krüger Marcello Moccia Brit Mollenhauer Wolfgang Oertel Ulrike Suenkel Uwe Walter Karin Wirdefeldt Inga Liepelt-Scarfone Walter Maetzler Daniela Berg

A growing body of evidence supports a prodromal neurodegenerative process preceding the clinical onset of Parkinson's disease (PD). Studies have identified several different prodromal markers that may have the potential to predict the conversion from healthy to clinical PD but use considerably different approaches. We systematically reviewed 35 longitudinal studies reporting prodromal PD featur...

2011
Ida Torunn Bjørk Glenys A. Hamilton

This study analyzed nurses' perceptions of clinical decision making (CDM) in their clinical practice and compared differences in decision making related to nurse demographic and contextual variables. A cross-sectional survey was carried out with 2095 nurses in four hospitals in Norway. A 24-item Nursing Decision Making Instrument based on cognitive continuum theory was used to explore how nurse...

2012
Seung Oh HAN ChongSeok HYUN Hyeng Keun KOO

Abstract We test the power-law hypothesis in the KOSPI 200 futures market for limit order placements using the method proposed by Clauset, Shalizi and Newman (2009[3]). With the order data submitted in the market between March 17, 2003 and March 11, 2004, we find that limit order placements rarely pass the power-law hypothesis. This contrasts to the most of empirical results reported in other m...

2017
Steven J Schrodi

Diagnostic codes within electronic health record systems can vary widely in accuracy. It has been noted that the number of instances of a particular diagnostic code monotonically increases with the accuracy of disease phenotype classification. As a growing number of health system databases become linked with genomic data, it is critically important to understand the effect of this misclassifica...

2015
Masao Nagasaki Jun Yasuda Fumiki Katsuoka Naoki Nariai Kaname Kojima Yosuke Kawai Yumi Yamaguchi-Kabata Junji Yokozawa Inaho Danjoh Sakae Saito Yukuto Sato Takahiro Mimori Kaoru Tsuda Rumiko Saito Xiaoqing Pan Satoshi Nishikawa Shin Ito Yoko Kuroki Osamu Tanabe Nobuo Fuse Shinichi Kuriyama Hideyasu Kiyomoto Atsushi Hozawa Naoko Minegishi James Douglas Engel Kengo Kinoshita Shigeo Kure Nobuo Yaegashi Masayuki Yamamoto

The Tohoku Medical Megabank Organization reports the whole-genome sequences of 1,070 healthy Japanese individuals and construction of a Japanese population reference panel (1KJPN). Here we identify through this high-coverage sequencing (32.4 × on average), 21.2 million, including 12 million novel, single-nucleotide variants (SNVs) at an estimated false discovery rate of <1.0%. This detailed ana...

2015
Caisa Öster Susan Bäckström Ingrid Lantz Mia Ramklint

BACKGROUND In the education of professionals in psychiatry, one challenge is to provide clinical placements with opportunities for students to interact and have direct contact with patients. The aim of this study was to explore Swedish psychiatric patients' perspectives on student participation in their care. METHOD In a cross-sectional survey design, 655 adult psychiatric patients at a unive...

Journal: :Statistical applications in genetics and molecular biology 2012
Benjamin French Thomas Lumley Thomas P Cappola Nandita Mitra

The general availability of reliable and affordable genotyping technology has enabled genetic association studies to move beyond small case-control studies to large prospective studies. For prospective studies, genetic information can be integrated into the analysis via haplotypes, with focus on their association with a censored survival outcome. We develop non-iterative, regression-based metho...

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