This paper describes the design and evaluation of a robust integrator for software-implemented control systems. The integrator is constructed as a generic component in the Simulink design tool, and can thus be used for robust implementation of a wide range of control algorithms. The integrator is designed to support the failbounded failure model for transient bit-flips that may occur in the CPU...

Formation of the 3' end of RNA polymerase II-transcribed snRNAs requires a poorly understood group of proteins called the Integrator complex. Here we used a fluorescence-based read-through reporter that expresses GFP in response to snRNA misprocessing and performed a genome-wide RNAi screen in Drosophila S2 cells to identify novel factors required for snRNA 3'-end formation. In addition to the ...

Air quality models compute the transformation of species in the atmosphere undergoing chemical and physical changes. The numerical algorithms used to predict these transformations should obey mass conservation and positive definiteness properties. Among all physical phenomena, the chemical kinetics solver provides the greatest challenge to attain these two properties. In general, most chemical ...

converge to a unique solution of the IVP up to the boundary of U [1]. In general, φn may converge slowly to the exact solution. The Picard iteration based integrator described in this paper has three main advantages. The the integrator has arbitrary order, is time adaptive, and has dense output. Dense output refers to the integrator being able to take time steps of variable length without havin...

Leapfrog integration has been the method of choice in N-body simulations owing to its low computational cost for a symplectic integrator with second order accuracy. We introduce a new leapfrog integrator that allows for variable timesteps for each particle in large N-body simulations. Tests with single particles in fixed potentials show that it behaves as a symplectic integrator. We then examin...

Mansell is with the Health, Physical Education, and Recreation Dept, Lincoln University, Lincoln University, PA. Tierney is with the Dept of Kinesiology, and Krynetskiy and Mishra, the School of Pharmacy, Temple University, Philadelphia, PA. Driban is with the Division of Rheumatology, Tufts Medical Center, Boston, MA. Clegg is with the Dept of Athletics, George Washington University, Washingto...

S. L. Clegg, M. J. Kleeman, R. J. Griffin, and J. H. Seinfeld School of Environmental Sciences, University of East Anglia, Norwich NR4 7TJ, UK Department of Civil and Environmental Engineering, University of California, Davis CA 95616, USA Institute for the Study of Earth, Oceans and Space, and Department of Earth Sciences, University of New Hampshire, Durham, NH 03824, USA Department of Chemic...

The gross and light microscopical changes that occur in the synovial membrane in human chronic haemarthrosis are well documented (Key, 1932; Ghormley and Clegg, 1948; Collins, 1951; De Palma and Cotler, 1956; Rodnan, Brower, Hellstrom, Didisheim, and Lewis, 1959) and virtually every change seen in man has been reproduced in the experimental animal (Key, 1929; Young and Hudacek, 1954; Wolf and M...