We report the isolation of adherent, clonogenic, fibroblast-like cells with osteogenic and adipogenic potential from the blood of four mammalian species. These cells phenotypically resemble but are distinguishable from skeletal stem cells found in bone marrow (stromal stem cells, "mesenchymal stem cells"). The osteogenic potential of the blood-borne cells was proven by an in vivo transplantatio...

Giant cells fully permissive for human cytomegalovirus (HCMV) were found to circulate, at a variable proportion, in peripheral blood of 21 out of 25 immunocompromised patients with disseminated HCMV infection. Circulating endothelial giant cells (EGC) were identified by a specific monoclonal antibody of endothelial origin and shown to express immediateearly, early, and late viral proteins. Immu...

Circulating tumour cells (CTCs) can be detected in the blood of many patients with different types of early or advanced cancer using antibody-based assays or molecular methods. In many studies the detection and quantification of CTCs has been linked to unfavourable prognosis. CTC detection offers the opportunity for individualized risk assessment beyond that determined by TNM staging. However, ...

Stem cell therapy could be a promising option for the treatment of vascular diseases. The finding of stem/progenitor cells in circulating blood and the vessel wall indicates that endogenous (adult) stem cells have the ability to repair endothelial cells, thereby restoring the integrity of the vessel and most importantly its function. However, embryonic stem cells, which are a population of undi...

Abstract Exercise mobilizes angiogenic cells, which stimulate vascular repair. However, limited research suggests exercise-induced increase of endothelial progenitor cell (EPCs) is completely lacking in type 1 diabetes (T1D). Clarification, along with investigating how T1D influences increases other cells (hematopoietic cells; HPCs) and surface expression chemokine receptor 4 (CXCR4) 7 (CXCR7),...

Objective: To investigate the value of CTC clinical features and blood-related test indicators in renal cancer patients by detecting number circulating tumor cells (CTC) with cancer. Methods: analyze 59 cell carcinoma (RCC) admitted to Department Urology, Affiliated Hospital Chengde Medical College from May 2018 October 2019. According count (5 pcs/3.5 ml), they were divided into positive group...

We demonstrate a label free and high-throughput microbubble-based acoustic microstreaming technique to isolate rare circulating cells from cancer patients with capture efficiency of 94% while preserving cell functional integrity within 8 minutes.

this article reviews will focus on the concept and formation of micro particles (mps) in circulation and their role in transfusion medicine and immune system. mps are cell membrane derived vesicles which express markers of their parent cells and are found in circulation at low levels. exact functions of mps are unclear. in here, physiological almost all types of circulating mps including platel...