Obesity is a chronic, multifactorial disease with increasing worldwide prevalence. It characterized by excessive adipose tissue accumulation in the body, which decreases patient’s life expectancy and has been associated higher incidence of chronic degenerative diseases, including type 2 diabetes mellitus, systemic arterial hypertension, cancer, cardiovascular disease. Several investigations hav...

Introduction: Chronic mountain sickness (CMS) represents a syndrome of secondary polycythemia along with thrombocytopenia, altered hemorheology, pulmonary and systemic hypertension, and congestive heart failure, occurring due to hypobaric hypoxia-anoxia-induced erythropoiesis reported in both native mountain residents and new climbers after prolonged stays at high and extreme a...

Migraine is a neurovascular disorder that is characterized by unilateral, pulsatile headaches. Migraine due to its individual and social effects is known as a major cause of disability in the world. The main complication of this disease is chronification that is known as chronic migraine (CM). It seems that several factors contribute to migraine chronification such as age, female gender, obesit...

BACKGROUND Preliminary evidence has suggested the role of inflammation in development and prognosis of cardiovascular diseases and cancers. Most of the prognostic studies failed to account for the effects of co-morbid conditions as these might have raised the systemic inflammation. We used neutrophil lymphocyte ratio (NLR) as a measure of systemic inflammation and investigated its association w...

An altered hormonal or chronic systemic inflammatory milieu characterizing endometriosis may result in a higher risk of hypercholesterolemia and hypertension. Conversely, elevated low-density lipoprotein in hypercholesterolemia and chronic systemic inflammation resulting from hypertension may increase the risk of endometriosis. We assessed the association of laparoscopically confirmed endometri...

S ystemic hypertension remains an important risk factor for a variety of cardiovascular, renal and neurological diseases. It is well known that elevated blood pressure (BP) of any degree is a precursor to excessive morbidity and premature mortality. untreated hypertension predisposes to coronary artery disease (CAD), left ventricular hypertrophy (LVH), congestive heart failure (CHF), chronic ki...

Smoking has adverse effects on health, causing ischemic heart disease, stroke, chronic obstructive lung disease and cancers of the respiratory, gastrointestinal, pancreas, kidney and urinary tract. Smoking causes an acute increase in mean arterial pressure and heart rate. Chronic smoking reduces the renal plasma flow. There is clinical evidence that smoking has adverse effects on renal outcome ...

The main purpose of this investigation was to evaluate the dental status and the level of periodontal disease undergoing hemodialysis chronic renal dialysis (CRF). Chronic renal failure is relatively common and systemic abnormalities such as anemia, platelet disorders and hypertension as well as oral manifestations including xerostomia, uremic stomatitis, periodontal disease and maxillary and m...

OBJECTIVES Plasma levels of immunoreactive endothelin-1 (ET-1) are raised in chronic heart failure. Whether plasma ET-1 contributes to the haemodynamic derangement found in chronic heart failure is not known. We investigated the effects of exogenous ET-1 on the pulmonary and systemic vasculature in patients with left ventricular systolic dysfunction (LVD), with or without overt heart failure. ...

background : this study aimed to investigate the association of seven common inflammatory diseases with type 2 diabetes (t2d) in the chinese mainland population. methods : participants were recruited from a great swathe of mainland from 2009 to 2013 for the cohort study. the demographic characteristics between patients with t2d or with inflammatory diseases, including age, sex, smoking status, ...