نتایج جستجو برای: chronic mild stress

تعداد نتایج: 1008133  

Background and Aim: Patients with chronic diseases are markedly at the risk of psychiatric disorders, particularly depression and anxiety. Results of various researches have shown the effectiveness of cognitive behavioral stress management on depression and anxiety. The aim of the current study was a comparative effectiveness of cognitive behavioral stress management on “depression” and “anxiet...

2014
Silin Pang Huali Wu Qian Wang Minxuan Cai Weimin Shi Jing Shang

Chronic stress can affect skin function, and some skin diseases might be triggered or aggravated by stress. Stress can activate the central hypothalamic-pituitary-adrenocortical (HPA) axis, which causes glucocorticoid levels to increase. The skin has HPA axis elements that react to environmental stressors to regulate skin functions, such as melanogenesis. This study explores the mechanism where...

2016
Ren-Hong Du Jun Tan Xi-Yang Sun Ming Lu Jian-Hua Ding Gang Hu

BACKGROUND Emerging evidence indicates that NLRP3 inflammasome-induced inflammation plays a crucial role in the pathogenesis of depression. Thus, inhibition of NLRP3 inflammasome activation may offer a therapeutic benefit in the treatment of depression. Fluoxetine, a widely used antidepressant, has been shown to have potential antiinflammatory activity, but the underlying mechanisms remain obsc...

Journal: :European journal of pharmacology 2011
Carlos C Crestani Rodrigo F Tavares Franscisco S Guimarães Fernando M A Correa Sâmia R L Joca Leonardo B M Resstel

In the present study, we investigated the effects induced by fluoxetine treatment (10 mg/kg) for either 1 or 21 consecutive days on arterial pressure and heart rate basal levels, baroreflex activity, hemodynamic responses to vasoactive agents and cardiovascular responses to acute restraint stress. Mild hypertension was observed after 21 days of treatment, but not after administration for 1 day....

2017
Miaomiao Jia Chenxin Li Ying Zheng Xiaojing Ding Meng Chen Jianhua Ding Renhong Du Ming Lu Gang Hu

Background Leonurine is an active alkaloid that is extracted from Traditional Chinese Medicine Herba leonuri. Emerging evidence indicates that leonurine produces neuroprotective effects in ischemic stroke, Parkinson's disease, and Alzheimer's disease. However, the effect of leonurine in neuropsychiatric disorders, especially in major depression, remains unknown. Methods We used the chronic mi...

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