Abstract Purpose of Review Fibro-adipogenic progenitors were first characterized in 2010 and later found to contribute significantly muscle regeneration mediate degenerative changes following injury. These also have an influence on the rotator cuff muscle’s response chronic injury which is defined by fibrosis accompanied massive fatty degeneration. The purpose this review highlight progenitor c...

Abstract Aims To evaluate the acute and chronic patterns of myocardial injury among patients with coronavirus disease-2019 (COVID-19), their mid-term outcomes. Methods results Patients laboratory-confirmed COVID-19 who had a hospital encounter within Mount Sinai Health System (New York City) between 27 February 2020 15 October were evaluated for inclusion. Troponin levels assessed 72 h before 4...

Over the last four decades, chronic ethanol feeding studies in rodents using either ad libitum feeding or intragastric infusion models have significantly enhanced our understanding of the pathogenesis of alcoholic liver disease (ALD). Recently, we developed a chronic plus binge alcohol feeding model in mice that is similar to the drinking patterns of many alcoholic hepatitis patients: a history...

BACKGROUND Parkinson's disease (PD) motor symptoms are frequently asymmetric and the factors that influence the side of onset are unclear. OBJECTIVE To explore whether peripheral injury and associated chronic limb pain may influence the side of onset. METHODS We administered a questionnaire to 128 PD patients in a tertiary movement disorder clinic. Handedness, date and type of limb injury(s...

Introduction: The use of polyethylene glycol-based solutions is the gold standard for bowel preparation colonoscopy. However, glycol might be associated with risk acute kidney injury. We aim to find out injury and factors development in patients using colonoscopy.Materials Methods: This was an observational study conducted Department Nephrology Gastroenterology, Bir hospital. Patients who under...

Idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) are chronic, progressive and lethal lung diseases. The incidence of IPF and COPD increases with age, independent of exposure to common environmental risk factors. At present, there is limited understanding of the relationship between ageing and the development of chronic lung diseases. One hypothesis is that ch...

BACKGROUND Studies of kidney disease associated with cardiac catheterization typically rely on billing records rather than laboratory data. We examined the associations between percutaneous coronary interventions, acute kidney injury, and chronic kidney disease progression using comprehensive Veterans Affairs clinical and laboratory databases. METHODS AND RESULTS Patients undergoing percutane...

Subtherapeutic antibiotics have been widely used in agriculture since the 1950s, which can be accumulated in human body through various approaches and may have long-term consequences. However, there is limited information about the link between chronic subtherapeutic antibiotic exposure and the outcome of ischemic brain injury. Here we showed that long-term treatment with subtherapeutic chlorte...

BACKGROUND Levels of MBCK can be increased in patients with skeletal muscle injury or renal failure in the absence of myocardial injury, causing diagnostic confusion. This study was designed to determine whether measurement of cardiac troponin I (cTnI), a myocardial regulatory protein with comparable sensitivity to MBCK, has sufficient specificity to clarify the etiology of MBCK elevations in p...