BACKGROUND The recommended first-line therapy of chronic urticaria is second-generation antihistamines, but the modalities of treatment remains unclear. Numerous recommendations with heterogeneous conclusions have been published. We wondered whether such heterogeneous conclusions were linked to the quality of published studies and their reporting. OBJECTIVE To review the study design and qual...

Urticaria, defined by the presence of wheals and/or angio-edema, is a common condition in children, prompting parents to consult physicians. For its successful management, paediatric-specific features must be taken into account, regarding the identification of eliciting triggers and pharmacological therapy. This review systematically discusses the current best-available evidence on spontaneous ...

Methods Two hundred and fifty four patients aged 13-80 years (202 females,79.5%), with chronic urticaria/angioedema who receive care at the Allergy Clinic of the Clinical Hospital of Ribeirão Preto Medical School in Brazil, were evaluated prospectively. Patients were inquired about triggering of symptoms by medications and/or physical agents and presence of anaphylaxis. In addition, they were i...

Urticaria is a kind of skin rash that sometimes caused by allergic reactions. Acute viral infection, stress, pressure, exercise and sunlight are some other causes of urticaria. However, chronic urticaria and angioedema could be either idiopathic or caused by autoimmune reaction. They last more than six weeks and could even persist for a very long time. It is thought that the level of C-reactive...