3p abnormalities are the most frequent chromosome abnormalities in small cell lung cancer (SCLC). To date these abnormalities have only been observed in cells derived from tumor tissues. It is thought that cancer-related chromosome abnormalities in peripheral lymphocytes could help to predict cancer development, prognosis, and future metastasis. We report clonal and nonclonal 3p abnormalities i...

objective: experiments were conducted to find the differences between post-thaw viability and chromosome aberrations in eight-cell mouse embryos at presence of dimethyl sulfoxide (dmso) and 1, 2-propanediol (proh) as croprotectants in different storage durations. materials and methods: in this case-control study, a total number of 720 mouse embryos from about 250 nmri mice were vitrified with 3...

1. Chromosome disorders Chromosome disorders are disorders due to abnormalities in structure or number of chromosomes. STRUCTURAL CHROMOSOME ABNORMALITIES Sometimes, chromosomes break, leading to 5 types of changes in chromosome structure 1. Deletion 2. Duplication 3. Inversion 4. Translocation 5. Insertion 1. Deletion: loss of portion of one chromosome. When this chromosome is passed on to off...