نتایج جستجو برای: chromogenic in situ hybridization cish

تعداد نتایج: 16982322  

Journal: :Fishes 2022

The vasa gene is essential for germ cell development and gametogenesis both in vertebrates invertebrates. In the present study, (Rcvasa) cDNA was cloned from cobia (Rachycentron canadum) using RACE amplification method. We found that full-length sequence of Rcvasa comprises 2571 bp, containing a 5′-UTR 145 3′-UTR 341 an open reading frame (ORF) 2085 encoding protein 694 aa. deduced amino acid c...

Journal: :American journal of clinical pathology 2010
Sanja Dacic Samuel A Yousem

The development of molecular targeted therapies with small-molecule inhibitors of the epidermal growth factor receptor (EGFR) has resulted in new therapeutic options for patients with advanced stage lung cancer. Certain clinical characteristics have been associated with an increased likelihood of response to EGFR tyrosine kinase inhibitors (TKIs; women, never smokers, East Asian ethnicity, and ...

Journal: :American journal of clinical pathology 2009
J M S Bartlett Fiona M Campbell Merdol Ibrahim Peter Wencyk Ian Ellis Elaine Kay Yvonne Connolly Anthony O'Grady Silvana Di Palma Jane Starczynski John M Morgan Bharat Jasani Keith Miller

Our purposes were to perform a robust assessment of a new HER2 chromogenic in situ hybridization test and report on concordance of silver in situ hybridization (SISH) data with fluorescence in situ hybridization (FISH) data and on intraobserver and interlaboratory scoring consistency. HER2 results were scored from 45 breast cancers in 7 laboratories using the Ventana (Tucson, AZ) INFORM HER-2 S...

2012
Fausto J. Rodriguez Brent A. Orr Keith L. Ligon Charles G. Eberhart

Microvascular proliferation is a key biological and diagnostic hallmark of human glioblastoma, one of the most aggressive forms of human cancer. It has recently been suggested that stem-like glioblastoma cells have the capacity to differentiate into functional endothelial cells, and that a significant proportion of the vascular lining in tumors has a neoplastic origin. In principle, this findin...

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