نتایج جستجو برای: chordoma
تعداد نتایج: 1277 فیلتر نتایج به سال:
Clival chordoma is a rare intracranial neoplasm located in the clivus with bony extension and destruction. It is difficult to resect completely and generally has a poor prognosis. However, intradural clival chordomas have been reported with good surgical outcomes. We present a rare case of intradural chordoma and a review of the literature.
BACKGROUND AND PURPOSE Chordoma is a relatively rare tumor of the skull base and sacrum thought to originate from embryonic remnants of the notochord. Chordomas arising from the skull base/clivus are typically locally aggressive with lytic bone destruction. When chordomas occur in an extraosseous location, they may mimic other lesions of the nasopharynx. We present 5 cases of primarily extraoss...
BACKGROUND Clival chordomas are a rare type of cancer with low metastatic potential and primary metastasize to the lung or bones. CASE DESCRIPTION This case report describes a possible metastatic, paravertebral chordoma at level C4-C5 in a patient with a past medical history of a clival chordoma. CONCLUSION Chordomas are unpredictable and may metastasise.
BACKGROUND The majority of chordomas show activation of the platelet-derived growth factor receptor (PDGFR). Based on in vitro intertumoral variation in response to recombinant PDGF protein and PDGFR inhibition, and variable tumor response to imatinib, we hypothesized that chordomas resistant to PDGFR inhibition may possess downstream activation of the pathway. METHODS Molecular profiling was...
Received June 24, 2017. Accepted June 26, 2017. Correspondence to: Young Bok Lee Department of Anesthesiology and Pain Medicine, Wonju College of Medicine, Ilsanro 20, Wonju 26426, Korea Tel: +82-33-741-1536, Fax: +82-33-742-8198, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecomm...
Introduction: Chordoma is a rare bone tumor, which develops mainly from the sacrum, the base of skull, or spine. Surgery + radiotherapy (if necessary) the standard treatment. Data on chordoma are scarce in this region, and thus, here we summarized 9 patients with this tumor whom treated institute. Material: Nine chordoma were summarized, who National Institute of Oncology Rabat between 201...
Chordoma is a rare malignant bone tumour with a poor prognosis and limited therapeutic options. We undertook a focused compound screen (FCS) against 1097 compounds on three well-characterized chordoma cell lines; 154 compounds were selected from the single concentration screen (1 µm), based on their growth-inhibitory effect. Their half-maximal effective concentration (EC50 ) values were determi...
Chordomas are rare, locally-aggressive tumours with a high rate of local recurrence. Recurrence along the route of surgical entry is an uncommon form of treatment failure. We report a case of a 59-year-old female who presented with a 3 cm neck mass in the left mid-sternocleidomastoid region. She had a history of a large clival chordoma resected via a transcervical, transparotid and transoral ap...
An unusual case of entirely infrasellar craniopharyngioma mimicking a clival chordoma is described. Only 22 cases of craniopharyngioma with nasopharyngeal extension have been reported in the literature. Of the reported cases, most were primarily intracranial with secondary downward extension; only two were thought to originate from an infrasellar location. The present case is another example of...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید