Rupture of chordae tendineae resulting in acute mitral regurgitation has previously been described following rheumatic fever, subacute bacterial endocarditis, blunt chest trauma, and in Marfan's syndrome. Chordae may rupture spontaneously in older patients, producing a characteristic clinical syndrome, but such 'idiopathic' rupture is exceptional before the age of 50. This paper reports the occ...

The time course of structural changes in fungiform papillae was analyzed in rats that received unilateral chorda tympani nerve transection at 10 days of age. Morphological differences between intact and denervated sides of the tongue were first observed at 8 days postsection, with an increase in the number of fungiform papillae that did not have a pore. In addition, the first papilla with a fil...

Chordae tendineae from 50 normal mitral valves were studied. Four main types can be distinguished by their mode of insertion. Commissural chordae insert into and define the commissures between the anterior and posterior leaflets. Rough zone chordae insert into the ventricular aspect of the distal rough portion of the anterior and posterior leaflets. Such rough zone chordae typically split into ...

This was a 45-year-old woman that initially consulted for a progressive hearing loss and dizziness of some 6 months of evolution. There were no notable relevant antecedents, while in the physical examination the otoscopy showed a greyish image that protruded in the posterior tympanic areas (Fig. 1a). The preoperative audiometry reflected a nixed right hearing loss with a mean loss in conversati...

Beidler's work in the 1950s showed that anions can strongly influence gustatory responses to sodium salts. We have demonstrated "anion inhibition" in the hamster by showing that the chorda tympani nerve responds more strongly to NaCl than to Na acetate over a wide range of concentrations. Iontophoretic presentation of Cl- and acetate to the anterior tongue elicited no response in the chorda tym...

5'-Ribonucleotides such as sodium 5'-inosinate (5'-IMP) , sodium 5'-guanylate (5'-GMP) and sodium 5'-xanthylate possess strong flavor-enhancing ability for humans when they are added in a minute quantity to monosodium glutamate (MSG), but little enhancement of taste occur by the addition of sodium 5'-uridylate (5'-UMP) and 5'-cytidylate (5'-CMP) to MSG5). ADACHI1) showed enhancement of the resp...

Isolated tricuspid insufficiency can be a well-tolerated lesion, as illustrated by a 32year follow-up in one patient reported here. A second case of recent onset is also described. The 13 reported cases of isolated tricuspid insufficiency due to trauma can be divided into two groups: ruptured papillary muscle or ruptured chordae tendineae and/or valve. All patients with ruptured papillary muscl...

This report describes a spectrum of M-mode and cross-sectional echocardiographic abnormalities in eight patients with infective endocarditis of the tricuspid valve. The M-mode echocardiogram of the tricuspid valve was abnormal in all but one patient in whom abnormal echoes were seen anterior to the tricuspid valve, in the right ventricular cavity and right ventricular outflow tract. Six patient...

Phonocardiographic, hemodynamic, angiographic, and cardiac echographic studies have been performed on 11 patients whose diseased mitral valves have been replaced by a supported aortic valve homograft. The chordae tendineae and papillary muscles were removed in all patients during the operation. Apical first heart sounds of normal intensity were present in all patients after surgery. Nine patien...