نتایج جستجو برای: cholesterolemia

تعداد نتایج: 210  

2017
Daisaku Masuda Shizuya Yamashita

Serum concentrations of low-density lipoprotein (LDL) cholesterol and total cholesterol (TC) are influenced by cholesterol production from the liver and cholesterol absorption in the intestine. As shown in an epidemiological study, both decreased cholesterol synthesis and increased cholesterol absorption in the intestine are significant and independent predictors of prevalent coronary heart dis...

2016
Hirofumi Ohnishi Shigeyuki Saitoh Hiroshi Akasaka Tetsuaki Furukawa Mitsuru Mori Tetsuji Miura

BACKGROUND We investigated the effect of longitudinal status change in metabolic syndrome (MetS) assessed by two different criteria on new onset of type 2 diabetes (NODM) in a Japanese population. METHODS The participants were 827 non-diabetic citizens who had undergone medical examinations in 1994 and 2003 or 2004. We used two different criteria of MetS: the interim criteria by 6 institution...

2014
Taku Ito Akatsuki Kokaze Mamoru Ishikawa Naomi Matsunaga Kanae Karita Masao Yoshida Tadahiro Ohtsu Hirotaka Ochiai Takako Shirasawa Hinako Nanri Hiromi Hoshino Yutaka Takashima

BACKGROUND Longevity-associated mitochondrial DNA 5178 (Mt5178) C/A reportedly modulates the effects of coffee consumption on the risk of hypertension, dyslipidemia and abnormal glucose tolerance, and those of alcohol consumption on the risk of hypertension, dyslipidemia and hyperuricemia in middle-aged Japanese men. However, there has been no research examining whether Mt5178 C/A polymorphism ...

Journal: :Circulation research 1999
T Kita

Our understanding of the molecular mechanism of atherosclerosis has changed during the past 20 years. A large variety of different risk factors such as smoking, shear stress, hypertension, hypercholesterolemia, diabetes mellitus, and obesity lead to endothelial activation and/or dysfunction, which can elicit a series of cellular interactions that culminate in the lesions of atherosclerosis. To ...

Journal: :Journal of lipid research 1960
J C SEIDEL N NATH A E HARPER

Interrelationships among the effects of dietary protein, sulfur-containing amino acids, and choline on the serum cholesterol concentration of the rat have been studied. Hypercholesterolemia was induced by feeding rats a diet containing cholesterol, cholic acid, and saturated fat. When the diet contained choline, additional casein alleviated the hypercholesterolemia. A similar effect was obtaine...

2011
Yinyuan Ding Ling Zhang Yuhui Wang Wei Huang Yin Tang Lu Bai Colin J. D. Ross Michael R. Hayden George Liu

BACKGROUND Macrophage-derived lipoprotein lipase (LPL) has been shown uniformly to promote atherosclerotic lesion formation while the extent to which it affects plasma lipid and lipoprotein levels varies in wild-type and hypercholesterolemic mice. It is known that high levels of LPL in the bulk of adipose tissue and skeletal muscle would certainly mask the contribution of macrophage LPL to meta...

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