Chronic nicotine (NIC) pretreatment has been shown to enhance NICinduced locomotor stimulation, an effect that seems critically dependent on activation of brain dopamine (DA) systems. In the present study the effects of chronic, intermittent NIC treatment were examined in the rat to establish whether such behavioral sensitization is associated with specific, regional changes in brain dopaminerg...

The pharmacokinetic studies of enrofloxacin were investigated in yak (Bos grunniens L.) after administration of enrofloxacin by intramuscular route at 5 mgkg-1 body weight. Blood samples were collected from the jugular vein at predetermined time intervals after drug administration. Plasma was separated and analysed for enrofloxacin by reverse-phase high performance liquid chromatography. Variou...

The study was conducted to evaluate hydraulic conductivity functions in relation to some soil chemical properties in an oxisols of the tropics. Field and laboratory studies were carried out and data collected, subjected to statistical analytical procedure for computing coefficient of variability and correlation among soil properties. Results of the study showed that hydraulic conductivity funct...

Nitric oxide (NO) has been implicated in large number of pathologies ad in normal physiological function of the brain. The aim of this study was to recognize the effect of Nitro-L-Arginine Methyl Ester mHC1 (NAME) and L-Arginine Ethyl Ester.HC1 (ARGININE) on reactivity of the central DA Dg receptor to agonist (Quinpirole) in rats. For this reason we have been used specific behavioural procedure...

Daily intraperitoneal injection of cyclophosphamide (CPA) (50 mgkg(-1) of body weight) for 5 days resulted in reduced levels of marrow and blood cellularity, which was most pronounced in 18 days post-treatment (pt). On day 18 after CPA treatment the enhancedlevels of nitric oxide (NO) precursors and metabolites (L-arginine, L-citrulline, reactive nitrogen species (RNS)) of marrow and blood cell...

A percepção dolorosa, avaliada funcionalmente através do sistema analgésico endógeno, reflete a atividade nociceptivo, o qual depende nível de excitabilidade nervoso, portanto, procura vias e formas que reduzam deste tornou-se uma preocupação humana para assim aliviar da dor. Objetivo: Determinar limiar excitação nociceptivo em animais (camundongos) submetidos tratamento com diferentes doses cl...

Medicinal plants may provide valuable therapeutic agents in modern medicine and traditional system, especially areas where the drugs are unavailable, expensive or predispose to life threatening complications. One of these is Garlic (Allium L. liliaceae) which used as foodstuff, condiment, flavoring folk medicine. The aim this study was investigate effect garlic juice on plasma glucose concentra...

there are many remediating methods for the polluted soils but only phytoremediation is a cost effective, environmental friendly, aesthetically pleasing approach that is most suitable for many countries. the purpose of this study was to investigate the potential of native plants for phytoremediation of contaminated soils with lead, zinc, cadmium and nickel in the rangelands around national lead ...