continuous four hours eeg (electroencephalogram) recordings and its power spectrum analysis using fast fourier transform (fft) in urethane anesthetized male charles foster rats were performed in two groups: open brain injury and p-cpa (para-chlorophenylalanine) pretreated before brain injury, respectively, and compared with the eeg power spectrum of control rats. the eeg power spectrum analysis...

Following the intraventricular injection of 5-hydroxytryptamine into the lateral ventricles of conscious mice, the concentration of brain lactate rose immediately but then decreased significantly compared with the saline injected controls. The concentration of brain glucose increased 20 min after the injection of 5-hydroxytryptamine. These effects of 5-hydroxytryptamine on lactate and glucose w...

The effects of p-CPA (para-chlorophenylalanine) pretreatment was studied on the sleep-wake parameters and patterns of behavioral activities in an animal model of acute immobilization stress. For the experiments, young male Charles Foster rats were divided into three groups, subjected to (i) acute immobilization stress for four hours on specially designed wooden boards, (ii) a similar model of a...

Effects of the tricyclic antidepressant clomipramine on plasma glucose levels in mice were studied. Clomipramine at doses ranging 5 - 20 mg/kg elicited significant hyperglycemia in mice. Hyperglycemia elicited by clomipramine was not reduced by pretreatment with the 5-hydroxytryptamine (5-HT) depleter p-chlorophenylalanine. The 5-HT(1/2/5/7)-receptor antagonist methysergide and the 5-HT(2A/2B/2...

Abstract The incidence rate of insomnia is increasing, but the mechanism it remains unclear. Warming Yang Strategy (WY) a kind Traditional Chinese Medicine, and proved to be effective in treating patients. animal was established with chlorophenylalanine (PCPA). Morris water maze open field test were performed evaluate influence WY on neurological recovery rats. TUNEL staining flow cytometry use...