DNA is a major cellular target of the vesicant chemical warfare agent sulfur mustard (SM, bis-(2-chloroethyl) sulfide). Others and we have proposed a possible role of apoptosis in SM vesication. Our results suggest that in SM-exposed human epidermal keratinocytes (HEK), DNA damage, DNA repair, and apoptosis may be interdependent. In HEK, SM causes cell death accompanied by caspase-3 activation ...

OBJECTIVE We aimed to quantify development assistance for health to countries of central and eastern Europe and the Commonwealth of Independent States (CEE-CIS). METHODS We used the International Development Statistics database of the Organisation for Economic Co-operation and Development and the database on development assistance for health compiled for the Commission on Macroeconomics and H...

A strong private equity market is a cornerstone for commercialization and innovation in modern economies. However, substantial differences exist in the relative amounts raised and invested in private equity across European countries. We investigate the macro-determinants of private equity investment in Europe, focusing on the comparison between CEE and Western European countries. Our estimation...

Background Previous studies have shown a steep learning curve in endotracheal intubation using the Airtraq(R) for non skilled personnel. We examined 16 Danish paramedics’ ability to intubate by using the Airtraq(R). The paramedics went through a 1-day course at CeMS (Centre for Medical Simulation, the department of Anaesthesia, Aalborg, Denmark) with skill training and simulation based teaching...

Abstract—The interdependences among stock market indices were studied for a long while by academics in the entire world. The current financial crisis opened the door to a wide range of opinions concerning the understanding and measurement of the connections considered to provide the controversial phenomenon of market integration. Using data on the log-returns of 17 stock market indices that inc...

In this paper we argue that ambiguity, combined with social opinion formation, can be used as the foundation of a game-theoretic equilibrium concept that transcends the standard Nash equilibrium concept, applied to a model of the tragedy of the commons. Our approach sheds light on the international environmental crisis and the relevant ongoing international negotiations. We conclude that social...

Four phenylalanine nitrogen mustards were tested against the S91 Cloudman mela noma in young male mice. Two of the mustards carried the di (2-chloroethyl) amino group in the meta position but differed in respect to the location of the amino group in the alanine side chain. Likewise, two of the mustards carried the di(2-chloroethyl)amino group in the para position, again differing, however, in l...