BACKGROUND Recent trials in Bangladesh, Nepal, and Pakistan have shown that chlorhexidine is an effective antiseptic for umbilical cord care compared to existing community-based cord care practices. Because of the aggregate reduction in neonatal mortality in these trials, interest is high in introducing a 7.1% chlorhexidine digluconate liquid or gel that delivers 4% chlorhexidine for umbilical ...

Twenty surgical staff members participated in a clinical trial to compare the microbiology and skin condition of hands when using a traditional surgical scrub (TSS) with a detergent-based antiseptic containing 4% chlorhexidine gluconate (CHG) and a short application without scrub of a waterless hand preparation (HP) containing 61% ethyl alcohol, 1% CHG, and emollients. The HP was associated wit...

Chlorhexidine gluconate (CHG) is a topical antiseptic used in a myriad of clinical settings. Recently, CHG baths have been shown to decrease multidrug-resistant organism acquisition and infections and catheter-associated bloodstream infections. The present study examined the effects of daily bathing with CHG on the recovery and antimicrobial susceptibility of cultivable cutaneous bacteria. The ...

BACKGROUND Effective neutralization in testing hand hygiene preparations is considered to be a crucial element to ensure validity of the test results, especially with the difficulty to neutralize chlorhexidine gluconate. Aim of the study was to measure the effect of chemical neutralization under practical test conditions according to EN 1500. METHODS We have investigated two ethanol-based han...

AIM To evaluate microleakage in resin composite restorations after antimicrobial pre - treatments. MATERIALS AND METHODS Forty freshly extracted non carious human premolars were procured. In all forty premolar specimens, class V preparation of standard dimension were prepared and were randomly divided into three experimental and one control group. In all control and experimental groups the cl...

Introduction: Oil pulling is described in ayurvedic literature as an oral hygiene practice. Chlorhexidine (CHX) considered the “gold standard” among mouthwashes.Aim: To compare efficacy of oil and chlorhexidine mouthwash on maintenance plaque control patients age group 14-25 years with gingivitis undergoing fixed orthodontic treatment.Methods: A total 30 subjects therapy mild to moderate induce...

Ten strains of Flavobacterium meningosepticum were isolated from routine clinical material during a period of two years. Of a number of antibiotics tested, clindamycin was the only one to which they were fully sensitive. The organism was found in chlorhexidine gluconate (Hibitane) solutions in use on the wards for the storage of thermometers and for routine disinfection.

Objective: As public distribution of a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is in underway, prevention disease 2019 (COVID-19) relies on minimizing spread. In this study, chlorhexidine gluconate was investigated as topical antimicrobial agent SARS-CoV-2. Methods: This randomized, prospective cohort study using an oral rinse and posterior oropharyngeal spr...

The aims of endodontic treatment in cases of apical periodontitis are to reduce as much as possible the number of microorganisms inside the root canal system and to inactivate toxins produced by them. Chlorhexidine has a wide spectrum of antimicrobial activity and is known for its property of substansivity. It is also known that dentin exerts a buffering effect under wide pH variations, and may...