نتایج جستجو برای: children thalassemia
تعداد نتایج: 482727 فیلتر نتایج به سال:
Background: Thalassemia represents a serious health problem in Iran because of its heterogeneous frequency and the existing endogamy system. It is an inherited blood disease characterized by the under production of normal hemoglobin, the oxygen-carrying protein in red blood cells. Materials and Methods: In this study, serum antioxidants including selenium (Se), zinc (Zn) and copper (Cu) were m...
Background: Previous evidences have been demonstrated that serum zinc deficiency in thalassemia major (TM) children is probably due to increase of zinc excretion, elevated ferritin level and desferal consumption or hepatic dysfunction. The aim of this study is determination of serum zinc concentration in thalassemia major children. Material and methods: This study has been carried on 77 childr...
Background: Thalassemia, a congenital disorder of hemoglobin synthesis is characterized by low and high iron status, prevalent in Bangladesh. Iron, consumed through drinking groundwater also increases the population status The study examined effect containing micronutrient powder (MNP) on ferritin Bangladeshi children with thalassemia their non-thalassemia peers exposed to concentration from gr...
BACKGROUND Knowledge of factors associated with quality of life in patients with thalassemia is necessary for creating appropriate clinical programs, social support, and improving treatment outcomes. The purpose of this study was to determine quality of life in children with thalassemia major at Center for Special Diseases of valiasr hospital in Birjand. MATERIALS AND METHODS This cross-secti...
BACKGROUND In hospital-based studies, alpha(+)-thalassemia has been found to protect against severe, life-threatening falciparum malaria. alpha(+)-Thalassemia does not seem to prevent infection or high parasite densities but rather limits progression to severe disease--in particular, severe malarial anemia. We assessed to what extent alpha(+)-thalassemia influences the association between mild,...
OBJECTIVE Cardiac failure due to iron overload remains the most common cause of death in patients with beta-thalassemia major. This study aimed to evaluate myocardial function in children with beta-thalassemia major using standard echocardiography technique and strain rate imaging. MATERIALS AND METHODS Conventional echocardiographic analysis, tissue velocity imaging, and strain/strain rate i...
A pedigree was studied in which five individuals with fl-thalassemia minor were found to have nontransfusional hemochromatosis. Three were children under the age of 10 and two were young male adults. ages 28 and 33. A 5-yr-old child without evidence of thalassemia also had hemochromatosis. Since hemochromatosis is transmitted as an HIA-linked autosomal recessive disorder. HLA haplotypes serve a...
s / Biol Blood Marrow Transplant 21 (2015) S206eS239 S239 was 11%. Incidence of chronic GVHD was 20%, severe chronic GVHD was 4%. 5 children died due to transplant related mortality (TRM), all of them were class 3 Thalassemia; 2 patients transplanted from unrelated donor and unrelated cord and 2 died after second HSCT. Causes of deaths were severe infections secondary to engraftment failure; se...
Zinc (Zn) is essential for appropriate growth and proper immune function, both of which may be impaired in thalassemia children. Factors that can affect serum Zn levels in these patients may be related to their disease or treatment or nutritional causes. We assessed the serum Zn levels of children with thalassemia paired with a sibling. Zn levels were obtained from 30 children in Islamabad, Pak...
Hb E/b thalassemia is the most common b thalassemia syndrome in Asia-Pacific due to a high prevalent of Hb E and b thalassemia genes. Management of this condition can be cumbersome due to its clinical heterogeneity and various disease severity ranging from severe end in which patients are transfusion dependent thalassemia (TD) similar to that of b thalassemia major (TM) to moderate and mild sev...
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