PURPOSE This article describes an empirically derived mathematical model of the treatment dose-response of occlusion therapy for amblyopia based on outcome data obtained from the Monitored Occlusion Treatment for Amblyopia Study (MOTAS). METHODS The MOTAS protocol comprised three discrete phases: baseline, refractive adaptation, and occlusion. Only data from the occlusion phase were used in t...

PURPOSE Anisometropia is a common cause of amblyopia. The relationship between anisometropia, patient age, and the development of amblyopia is unknown. Photoscreening identifies children with anisometropia in a manner that is not biased by visual acuity and allows a unique opportunity to evaluate how patient age influences the prevalence and depth of anisometropic amblyopia. METHODS A statewi...

Self-perception of School-aged Children With Amblyopia and Its Association Reading Speed Motor Skills

PURPOSE It has previously been shown that anisometropic amblyopia affects the programming and execution of saccades. The aim of the current study was to investigate the impact of strabismic amblyopia on saccade performance. METHODS Fourteen adults with strabismic amblyopia, 13 adults with strabismus without amblyopia, and 14 visually normal adults performed saccades and reach-to-touch movemen...

PURPOSE To elucidate the different neuromechanisms of subjects with strabismic and anisometropic amblyopia compared with normal vision subjects using blood oxygen level-dependent functional magnetic resonance imaging (BOLD-fMRI) and pattern-reversal visual evoked potential (PR-VEP). METHODS Fifty-three subjects, age range seven to 12 years, diagnosed with strabismic amblyopia (17 cases), anis...

Introduction: Strabismic amblyopia is frequently encountered by pediatric ophthalmologists and orthoptists. An understanding of its onset and of the timing of treatment may lead to better long-term treatment results. Methods: A review was conducted of past and recent literature pertaining to strabismic amblyopia. Articles relevant to further understanding the onset, course, and management of st...

Amblyopia is a visual disorder caused by poorly coordinated binocular input during development. Little is known about the impact of amblyopia on the white matter within the visual system. We studied the properties of six major visual white-matter pathways in a group of adults with amblyopia (n=10) and matched controls (n=10) using diffusion weighted imaging (DWI) and fiber tractography. While w...

BACKGROUND Amblyopia is an acquired defect of vision caused by abnormal visual experience that occurs during childhood. Since early diagnosis is important in preventing further irreparable effects, the aim of this study was to investigate the outcome of amblyopia screening in children. METHODS Data from the amblyopia screening program in the Welfare Department of Bandar Abbas during 2011-2012...

PURPOSE To test the hypothesis that eyes with amblyopia may have thicker retina, retinal nerve fiber layer thickness (RNFLT) was investigated in patients with unilateral amblyopia. METHODS Thirty-eight patients with unilateral amblyopia were studied. Among them, 20 patients had amblyopia with strabismus and 18 had refractive amblyopia without strabismus. Nineteen of 38 had anisometropia of 2....

Amblyopia is reduction of vision with the proper optical correction either in one or both eyes.. The diagnosis of Amblyopia requires both the demonstration of visual acuity loss and the absence of an organic cause. A visual defect screening program was conducted on children aged 3-14 years of Bope-Poddala health unit area of the city of Galle Sri Lanka. Children aged 5-14 years were examined at...