The presence of too many or too few centrosomes at mitosis can disrupt the timely formation of a bipolar spindle and may lead to aneuploidy and cancer. Strict control of centrosome duplication is therefore crucial. Centrosome duplication must occur once per cell cycle and the number of new centrioles made must be tightly controlled. The importance of protein degradation for the orderly progress...

In this research at the first, xylometazoline hydrochloride drug (XY) and its fullerene connected form (FXY) were optimized. Natural Bond Orbital (NBO) calculations for these compounds were carried out at the B3LYP/6-31G* quantum chemistry level, in the gas phase and the liquid phase. These calculations can be performed at different accuracy levels depending on the aim of the theoretical study....

In a confining, renormalisable, Dyson-Schwinger equation model of two-flavour QCD we explore the chemical-potential dependence of the dressed-quark propagator, which provides a means of determining the behaviour of the chiral and deconfinement order parameters, and low-energy pion observables. We find coincident, first order deconfinement and chiral symmetry restoration transitions at μc = 375M...

This Article addresses a critical but underexplored topic of “platform” law: if user’s online content or actions violate the rules, what should happen next? The longstanding expectation is that Internet services remove violative accounts from their services, and many laws mandate result. However, have wide range other options—what I call “remedies”—they can use to redress applicable rules. desc...

1 Department of Materials Science and Engineering, PennState University, PA 16802. Email: [email protected] Abstract – Engineering education often makes reference to historical “laws” dating back to a time when science was still at an early stage of development. An example is the principle of displacement and moderation of chemical equilibrium formulated by Le Chatelier in various forms betw...

After giving an overview of recently invented methods for simulating lattice QCD at small µ/T , we discuss some results for bulk thermodynamic quantities of QCD matter coming from those methods. We focus on the transition line and the critical endpoint in the QCD phase diagram.