Burn patients are immunocompromised yet paradoxically are able to effectively reject allogeneic skin grafts. Failure to close a massive burn wound leads to sepsis and multiple system organ failure. Immune suppression early (3 days) after burn injury is associated with glucocorticoid-mediated T cell apoptosis and anti-inflammatory cytokine responses. Using a mouse model of burn injury, we show C...

Burns expose the deeper tissues of the skin or body to invasive microbes. Topical preparations for treating burn wounds, to be useful, should ideally have antibiotic power and promote healing. Silver compounds have been the mainstay of topical burn treatment for decades. However, most chemical substances retard wound healing. Several natural agents such as honey and moist exposed burn ointment ...

PURPOSE To study the therapeutic potential of amniotic membrane transplantation in cases of severe acute chemical ocular burn and Stevens-Johnson syndrome. METHODS We retrospectively reviewed the records of eight patients, with a total of ten eyes, submitted to amniotic membrane transplantation for treatment of ocular chemical burns and Stevens-Johnson syndrome in the acute phase between Janu...

Pseudomonas aeruginosa is a severe opportunistic pathogen and is one of the major causes of hard to treat burn wound infections. Herein we have used an RNA-seq transcriptomic approach to study the behavior of P. aeruginosa PAO1 growing directly on human burn wound exudate. A chemical analysis of compounds used by this bacterium, coupled with kinetics expression of central genes has allowed us t...

Mortality rate of burn patients can serve as an objective criterion for quality control and as a measure for research and preventive programs. A prospective study of burn victims, from data of burn registry program, was conducted to determine the etiology, risk factors of mortality and outcome of pediatric burns. We had 514 patients below 15 years old. Burns caused by scalding were the most fre...

This review analyzes different scientific views on the diagnosis and treatment of chemical burns esophagus its consequences - formation cicatricial stenosis organ. Post-burn scar in pediatric surgery is a fairly common disease that formed children with burn 3rd degree. In study this pathology timely between degrees esophageal correct selection patients for dilatation organ particular interest p...

Silver nanostructures as an effective antibacterial materials were synthesized via three various hydrothermal, sono-chemical and microwave methods using water as a green solvent. Then Chitosan-Ag polymer based nanocomposites were made by a fast chemical procedure. The influence of power, temperature and time on the morphology and particle size of the products was investigated. Scanning electron...

Objective: This study attempts to document the current bacteriological profile from pertinent specimens of fire burn victims in our setting with respect to the time related variations in the isolation of microbial species, extent of their burn injury and their effect on mortality rate. Methodology: During a three year period (Jan 2008 to Dec 2010), a prospective study was conducted on 477 fire ...

OBJECTIVE The goal was to examine comprehensively the patterns and trends of burn-related injuries in children, adolescents, and young adults treated in US emergency departments between 1990 and 2006. METHODS Through use of the National Electronic Injury Surveillance System database, cases of nonfatal burn-related injuries were selected by using diagnosis codes for burns (scalds, thermal, che...

BACKGROUND Burn injuries are among the most devastating injuries seen in the emergency units. The epidemiology of this injury varies from one part of the world to another. This is a 3-year report in an attempt to provide information on the current epidemiology of burns in this center. METHOD Patients admitted into the University of Calabar Teaching Hospital, with burn injuries were prospectiv...