We describe a computational method, plane of best fit (PBF), to quantify and characterize the 3D character of molecules. This method is rapid and amenable to analysis of large diverse data sets. We compare PBF with alternative literature methods used to assess 3D character and apply the method to diverse data sets of fragment-like, drug-like, and natural product compound libraries. We show that...

In this paper, an audio-book, in which a professional voice talent performs multiple characters, is exploited to investigate the expressiveness of speech. The expressive speech space of the sole speaker is explored by finding the distances between acoustic models of multiple characters and the perceived proximity between their speech utterances. Using the speech of ten characters as test data, ...

For most algorithms dealing with sets of points in the plane, the only relevant information carried by the input is the combinatorial configuration of the points: the orientation of each triple of points in the set (clockwise, counterclockwise, or collinear). This information is called the order type of the point set. In the dual, realizable order types and abstract order types are combinatoria...

In this paper we present a new method for fusing classifiers output for problems with a number of classes M > 2. We extend the well-known Behavior Knowledge Space method with a hierarchical approach of the different cells. We propose to add the ranking information of the classifiers output for the combination. Each cell can be divided into new sub-spaces in order to solve ambiguities. We show t...

Gaussian scale-space is considered to be a modern bottom-up tool in computer vision. The Amer-ican and European vision community, however, is unaware of the fact that Gaussian scale-space has already been axiomatically derived in 1959 in a Japanese paper by Taizo Iijima. This result formed the starting point of an entire world of linear scale-space research in Japan ranging from various axiomat...

In this paper we propose “sound visualization” which provides a learning process for listeners considered as perceptual systems to perceive “character-related” sounds in a virtual 3D acoustic space. “Character-related” sound represents the most appropriate sound event to be perceived (“read”) even by the visually impaired. The test data (characters) used in our experiments were segmented from d...

' ABSTRACT O A major harrier to the human communication is attributed to the fact that there is no compatible typewriter, as in the Western World, for any non-alphabetic language outside of the Western World. This paper~11 describe how a plotter can be used through programming, as a universal graphic character writer for all non-alphabetic as well as alphabetic languages in place of the typewri...

In this article, we propose a novel stroke width transform (SWT) voting-based color reduction method for detecting text in natural scene images. Unlike other text detection approaches that mostly rely on either text structure or color, the proposed method combines both by supervising text-oriented color reduction process with additional SWT information. SWT pixels mapped to color space vote in ...

Recently, casting planning as propositional satisfiability has been shown to be a very promising technique for plan synthesis. Although encodings based both on statespace planning and on plan-space (causal) planning have been proposed, most implementations and trade-off evaluations primarily use state-based encodings. This is surprising given both the prominence of plan-space planners in tradit...

Ž . Recently some fast methods LAESA and TLAESA have been proposed to find nearest neighbours in metric spaces. The average number of distances computed by these algorithms does not depend on the number of prototypes and they show linear space complexity. These results where obtained through vast experimentation using only artificial data. In this paper, we corroborate this behaviour when appli...