Changes in intracellular Ca levels are an important signal underlying neuron-glia cross-talk, but little is known about the possible role of voltage-gated Ca channels (VGCCs) in controlling glial cell Ca influx. We investigated the pharmacological and biophysical features of VGCCs in cultured rat cortical astrocytes. In whole-cell patchclamp experiments, L-channel blockade (5 M nifedipine) redu...

introduction: side weir structures are extensively used in hydraulic engineering, irrigation and environmental engineering, and it usually consists of a main weir and a lateral channel. side weirs are also used as an emergency structure. this structure is installed on one side or both sides of the main channel to divert the flow from the main channel to the side channel. lateral outflow takes p...

[1] Data from laboratory flumes and natural streams show that the critical Shields stress for initial sediment motion increases with channel slope, which indicates that particles of the same size are more stable on steeper slopes. This observation is contrary to standard models that predict reduced stability with increasing slope due to the added downstream gravitational force. Processes that m...

Previous studies have demonstrated that the slope of the function relating the action potential duration (APD) and the diastolic interval, known as the APD restitution curve, plays an important role in the initiation and maintenance of ventricular fibrillation. Since the APD restitution slope critically depends on the kinetics of the L-type Ca(2+) current, we hypothesized that manipulation of t...

Triple Material (TM) Double Gate (DG) Metal Oxide Semiconductor Field Effect Transistor (MOSFET) with high-k dielectric material as Gate Stack (GS) is presented in this paper. A lightly doped channel has been taken to enhance the device performance and reduce short channel effects (SCEs) such as drain induced barrier lowering (DIBL), sub threshold slope (SS), hot carrier effects (HCEs), channel...

We present performance characteristics of nanoscaled cobalt phthalocyanine-based organic field-effect transistors (OFETs) as a function of channel length. We found a channel length range which maximizes the field effect mobility in a trade-off between the decrease in the number of organic grain boundaries and the increase of the electrode-organic contact region. Further reduction of channel len...

a r t i c l e i n f o The rapid expansion of high-spatial resolution optical sensors and imagery over the last decade presents exceptional opportunities for quantifying visible attributes of geomorphic systems. In this study, we detail a simple, robust methodology (ChanGeom) to extract continuous channel width and centerline datasets for single-thread channels using freely available high-spatia...