نتایج جستجو برای: chalcones
تعداد نتایج: 1021 فیلتر نتایج به سال:
A virtual screening analysis of our library of phytochemical structures with dengue virus protein targets has been carried out using a molecular docking approach. A total of 2194 plant-derived secondary metabolites have been docked. This molecule set comprised of 290 alkaloids (68 indole alkaloids, 153 isoquinoline alkaloids, 5 quinoline alkaloids, 13 piperidine alkaloids, 14 steroidal alkaloid...
Ethyl naphtho[2,1-b]furan-2-carboxylate (2) on reaction with hydrazine hydrate in presence of acid catalyst in ethanol medium affords naphtho[2,1-b]furan-2-carbohydrazide (3). The reaction of substituted acetophenones (4a-c) with aromatic aldehydes (5a-e) produces chalcones (6a-o) via the Claisen condensation. The reaction of naphtho[2,1-b]furan-2-carbohydrazide (3) with chalcones (6a-6o) in pr...
A new series of 2-(ortho & para substituted phenoxy)1-(3-(3-chloro-4-methoxyphenyl)-5-(substituted phenyl)-4,5dihydropyrazol-1-yl)ethanone were synthesized. Ortho and para substituted phenol was refluxed with ethylchloroacetate in dry acetone in presence of anhydrous potassium carbonate to yield ethyl (ortho & para substituted phenoxy) acetate (1). The substituted ester on reaction with hydrazi...
A series of chalcones a1-20 bearing a 4-OMe groups on the A-ring were initially synthesized and their anticancer activities towards HepG2 cells evaluated. Subsequently, a series of chalcones b1-42 bearing methoxy groups at the 2' and 6'-positions of the B-ring were synthesized and their anticancer activities towards five human cancer cell lines (HepG2, HeLa, MCF-7, A549 and SW1990) and two non-...
In this paper, the synthesis of two new chalcones with a donor-acceptor structure by Claisen-Schmidt condensation for photonic applications is presented. The characterization and evaluation optoelectronic properties are...
Some new heterocyclic compounds containing isoxazole, pyrazole and oxadiazole ring systems were prepared from various chalcones. The synthesized compounds have been characterized by elemental analysis and spectral methods. These compounds were screened for their antimicrobial activities.
An Efficient Protocol for Synthesis of 2-amino-3cyanopyridine Derivatives using Nano-modified SBA-15
Condensation reaction of chalcones with malononitrile and ammonium acetate in the presence of the green nano-modified SBA-15 affords the corresponding 2-amino-3-cyanopyridine derivatives in excellent yield. This approaches claimed to be an environment friendly protocol as it afforded some advantages such as excellent yields and cleaner reaction.
Yellow color in dahlia flowers is conferred from chalcones, butein and isoliquiritigenin. The intensity of yellow cultivars diverse, but a detailed study on this has not yet been performed. In study, we first identified structures flavonoids by nuclear magnetic resonance imaging ray florets the red-white bicolor ‘Shukuhai’, which contains flavones anthocyanins. Four anthocyanins, four flavone d...
It was found that TBD, a cheap and commercially available guanidine, easily catalysed the synthesis of biologically important 3,5-diarylpyrazolines from chalcones and acylhydrazines via a selective secondary amine alkylation.
We report an efficient silica-H2SO4 mediated synthesis of a variety of chalcones that afforded the targeted compounds in very good yield compared to base catalyzed solvent free conditions as well as acid or base catalyzed refluxing conditions.
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