To assess the effectiveness of continuous lumbar drainage (LD) for management of postoperative cerebrospinal fluid leaks after endoscopic endonasal transsphenoidal approach for resection of pituitary adenoma. Three hundred eighty-four medical records of patients who were admitted to our institute during a 2.5-year period were retrospectively reviewed, 33 of them experienced low-flow cerebrospin...

OBJECTIVE To assess circulating tumor cells in cerebrospinal fluid as a diagnostic approach to identify meningeal metastasis in patients with non-small cell lung cancer by using tumor marker immunostaining-fluorescence in situ hybridization (TM-iFISH). METHODS In 5 non-small cell lung cancer patients who were confirmed to have developed meningeal metastasis by cerebrospinal fluid cytology, 20...

Cerebral edema must be closely implicated in the cerebrospinal fluid production rate and corticosteroid, which is effective to reduce cerebral edema, must have influence upon the rates of the cerebrospinal fluid production in the edematous brain. There has been a little of previous studies which dealt with the influence of corticosteroid upon the cerebrospinal fluid production rate, but little ...

OBJECTIVE To review the incidence of cerebrospinal fluid leak after vestibular schwannoma removal reported in the literature. DATA SOURCES MEDLINE and PubMed literature search using the terms "acoustic neuroma" or "vestibular schwannoma," and "cerebrospinal fluid leak" or "cerebrospinal fluid fistula" covering the period from 1985 to the present in the English language literature. A review of...

There is evidence for a hypofunction of the hypothalamicpituitary-adrenal (HPA) axis in a proportion of the patients with chronic fatigue syndrome (CFS), despite the negative studies and methodological difficulties. In this review, we focus on challenge studies and on the role of the HPA axis in the pathogenesis of CFS. Mild hypocortisolism, blunted adrenocorticotropin response to stressors and...

Objective Cerebrospinal fluid (CSF), its secretion, circulation and absorption have been the subject of recent researches. There is a general agreement that the main site of CSF secretion is in the choroids plexus. However, the main absorption site is controversial. Some believe that arachnoid granulations are the principle sites of CSF absorption. In this study, different locations of CSF abs...