Objective(s): The use of antisense oligonucleotides (AOs) to restore normal splicing by blocking the recognition of aberrant splice sites by the spliceosome represents an innovative means of potentially controlling certain inherited disorders affected by aberrant splicing. Selection of the appropriate target site is essential in the success of an AO therapy. In this study, in search for a splic...

To ful ll the future demand for and increase the reliability of mobile cellular service, we have explored the use of a call admission policy that constitutes a dynamic channel allocation scheme for a cellular system. The call admission policy optimizes a weighted blocking criteria for a queueing network model of a mobile cellular system. In this context, the call admission problem is formulated...