alzheimer’s disease (ad) is a neurodegenerative disease that was characterized with deposit of beta amyloid (aβ) aggregate in senile plaque. oxidative damage to neurons and loss of cholinergic neurons in forebrain region are observed in this disease. melissa officinalis is a medicinal plant from lamiaceae family, used traditionally in the treatment of cognitive disorders. it has cholinomimetic ...

In the framework of tube model, survival fraction dilated tube, φʹ(t), is essential since relaxation entire system described according to this quantity. However, a method define it in multi-chain simulations has yet be considered. study, primitive chain network were performed, and few structural quantities discussed as possible candidates for use φʹ(t). Before analysis, simulation was evaluated...

background & aim: esophageal cancer is one of the main common causes of death. the high prevalence of esophageal cancer in northern iran is an important public health problem. the main aim of this paper was to assess the factors affecting survival of  atients with esophageal cancer in neighbor provinces around the caspian sea using weibull mixture cure model and mixture cure model based on a no...

Since 1957, broad proton beam radiotherapy with a spread out Bragg peak has been used for cancer treatment. More recently, studies on the use of proton therapy in the treatment of non-small cell lung cancer (NSCLC) were performed and although the benefit of using protons for the treatment of NSCLC is recognized, more work is needed to gather additional data for the understanding of cell respons...

Introduction: The aim of the present study was to assess the radiosensitivity parameters for SK-BR-3 (SKBR3) breast cancer cells that could be implemented in the cutting-edge treatment planning systems (TPS) for accelerated partial-breast irradiation (APBI). Materials and Methods: The cell survival fraction and its relevant radiosensitivity coefficients, namely α and β, in linear-quadratic (LQ)...

The Drosophila PDGF/VEGF receptor (PVR) has known functions in the guidance of cell migration. We now demonstrate that during embryonic hematopoiesis, PVR has a role in the control of antiapoptotic cell survival. In Pvr mutants, a large fraction of the embryonic hemocyte population undergoes apoptosis, and the remaining blood cells cannibalistically phagocytose their dying peers. Consequently, ...

background and objectives: ziziphora clinopodioides is a perennial herb and grows widely in west and northwest of iran. the aerial parts are used as appetizer, carminative and antiseptic as well as for the treatment of medical conditions such as high blood pressure, asthma hyperhidrosis, palpitation and insomnia methods: the aerial parts of ziziphora clinopodioides lam. were extracted by ethano...