A system to detect a minimal function of Saccharomyces cerevisiae centromeres in vivo has been developed. Centromere DNA mutants have been examined and found to be active in a plasmid copy number control assay in the absence of segregation. The experiments allow the identification of a minimal centromere unit, CDE III, independently of its ability to mediate chromosome segregation. Centromere-m...

O CDE no ensino de BIM
 Ambiente Comum Dados ou Common Data Environment (CDE) é um conceito cada vez mais citado nos processos trabalho em BIM e isto ocorre por diferentes fatores. Entre eles, o lançamento das duas primeiras partes da NBR ISO 19650 (2022), a qual recomenda expressamente que toda gestão informação se dê CDE, além recente difusão algumas plataformas digitais sob este título,...

Abstract Planning and approval processes in Germany still take many years some cases. According to the Federal Ministry for Digital Transport digitalization must be used pick up pace achieve progress. In this context, digital methods applications such as a Common Data Environment (CDE) promise accelerate increase efficiency of road construction projects. This paper first provides an illustratio...

Compact Evolutionary Algorithms (cEAs) have been developed in order to address optimization problems characterized by limited memory resources. This situation is typical of robotics and control problems where a full power computing device may be unavailable due to cost and/or space limitations. These algorithms do not store and process an entire population and all its individuals therein but ma...

This paper investigates the the development and evolution of concepts and the management of transformers, which adds semantics to the concepts. We illustrate how concepts, their variants and transformers can be developed via cooperation. In order to meet increasing user demands for more various software systems, we are revising the software developing process to accommodate mass customisation b...

The Architecture, Engineering, and Construction (AEC) industry is transitioning toward using cloud-based Common Data Environments (CDEs) with interlinked BIM models. A CDE that engages all stakeholders of the building's design, construction, operation phases represents outset maturity level 3. This article introduces a called Virtual Commissioning (VC), capable commissioning an HVAC system befo...

A central question in cell cycle control is how differential gene expression is regulated. Timing of expression is important for correct progression through the cell cycle. E2F, CDE, and CHR promoter sites have been linked to transcriptional repression in resting cells and activation during the cell cycle. Further, the DREAM complex binds CHR or CDE/CHR elements of G2/M genes resulting in repre...