cd226

Cristina Bottino Roberta Castriconi Daniela Pende Paola Rivera Marina Nanni Barbara Carnemolla Claudia Cantoni Jessica Grassi Stefania Marcenaro Nicolas Reymond Massimo Vitale Lorenzo Moretta Marc Lopez Alessandro Moretta

Human natural killer (NK) cells express a series of activating receptors and coreceptors that are involved in recognition and killing of target cells. In this study, in an attempt to identify the cellular ligands for such triggering surface molecules, mice were immunized with NK-susceptible target cells. On the basis of a functional screening, four mAbs were selected that induced a partial down...

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Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases

Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor

Expansion of circulating peripheral TIGIT+CD226+ CD4 T cells with enhanced effector functions in dermatomyositis

Hitting the complexity of the TIGIT-CD96-CD112R-CD226 axis for next-generation cancer immunotherapy

Requirement of the serine at residue 329 for lipid raft recruitment of DNAM-1 (CD226)

The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis

Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

Imbalance of the CD226/TIGIT Immune Checkpoint Is Involved in the Pathogenesis of Primary Biliary Cholangitis

CD226 gene polymorphisms are associated with non-small-cell lung cancer in the Chinese Han population

UPR decreases CD226 ligand CD155 expression and sensitivity to NK cell-mediated cytotoxicity in hepatoma cells