Hemagglutinating and complement-fixing antigens of La Crosse virus (California arbovirus group) were produced in serum-free suspension cultures of BHK-21/13S cells. The appearance and production of these antigens were correlated with the titer of infectious virus. No significant differences in antigen titers were produced by varying virus dose 10-fold. Hemagglutinin appeared 6 to 8 hr after ino...

The three-dimensional crystal structure of the complex between the Fab from the monoclonal anti-lysozyme antibody D1.3 and the antigen, hen egg white lysozyme, has been refined by crystallographic techniques using x-ray intensity data to 2.5-A resolution. The antibody contacts the antigen with residues from all its complementarity determining regions. Antigen residues 18-27 and 117-125 form a d...

Abbreviation AFP Alpha fetoprotein CD Cluster of differentiation CEA Carcino-embryonic antigen CHOP Cyclophosphamide, hydroxydaunorubicin (also called doxorubicin or Adriamycin), Oncovin (vincristine), prednisone CT Contrast tomography DLBCL Diffuse large B-cell lymphoma NHL Non-Hodgkin lymphoma IHC Immunohistochemistry MPO Myeloperoxidase LCA Leucocyte common antigen PV Per vagina PAP Papanico...

Submit Manuscript | http://medcraveonline.com Abbreviations: NDV: Newcastle Disease Virus; APMV-1: Avian Paramyxovirus Type I; IFN: Interferon; CTLA-4: Cytotoxic T Lymphocyte Associated Antigen-4; RCC: Renal Cell Carcinoma; HNSCC: Head and Neck Squamous Cell Carcinoma; IL-2: Interleukin-2; DTH: Delayed Type Hypersensitivity; Gy: Gray; BCG: Bacillus Calmette-Guerin; HN: Hemagglutinin-Neuraminida...

Coeliac disease (CD) is one of the most common diseases worldwide, resulting from a combination of environmental (gluten) and genetic (human leucocyte antigen (HLA) and non-HLA genes) factors. Depending on the geographical location, the prevalence of CD has been estimated to approximate 0.5-1%. The only treatment currently available for CD is a gluten-free diet (GFD) excluding gluten-containing...

We describe a surgical emergency due to GI-bleeding caused by gastrointestinal autonomic nerve tumours (GANT s) in a patient with von Recklinghausen s disease. A 72 year old female patient with von Recklinghausen s disease was admitted with maelena. Endoscopy showed no active bleeding in the stomach and the colon. Therefore an angio-CT-scan was performed which revealed masses of the proximal je...

A 72-year-old female presented with dyspepsia for 2 years and an incidental mass in the head of the pancreas on abdominal computed tomography (CT) scan. Patient had multiple negative endoscopic ultrasound guided biopsies. She was followed up for 3 years with serial imaging until an abdominal CT scan showed an increase in size of the pancreatic mass. Physical examination was unremarkable. Labora...

GIST tumors are the most frequent mesenchymal tumors in the gastrointestinal tract (1,2). There are between 10 and 20 cases per million in developed countries, and between 20 and 45% of them are malignant (3-5). These tumors are characterized by the expression of the membrane receptor c-KIT/CD 117 with tyrosine-kinase activity, synthesized from proto-oncogene c-KIT (1-6). The cKIT and CD 34 exp...

Myeloid sarcoma is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells and may precede or occur synchronously with acute myeloid leukemia. We reported a 35-year-old male of isolated myeloid sarcoma who presented with symptoms similar to chronic rhinosinusitis initially. Isolated myeloid sarcoma in the paranasal sinuses is exceedingly rare after reviewing th...