Prognostics is a method that permits the assessment of product reliability under its actual application conditions. While there are various methods to perform prognostics, including physics of failure and data-driven methods, these methods have some key disadvantages. This paper presents a fusion prognostics approach, which combines or “fuses together” the physicsof-failure and data-driven meth...

Determining battery lifetimes is beset with difficulties. Performance data are not generally available and costly to generate since large numbers of batteries must be tested to destruction. Furthermore, the required test period to verify the predictions is often greater than commercial decision lead time. While the reliability predictions in the following section are very useful, they are desig...

Congenital Hepatic Fibrosis (CHF) is a rare disease that affects both the liver and kidneys.  Congenital hepatic fibrosis (CHF) is an autosomal recessive inherited malformation defined pathologically by a variable degree of periportal fibrosis and irregularly shaped proliferating bile ducts. Affected individuals also have impaired renal function, usually caused, in children and teenagers, by an...

Although most patients with Takotsubo cardiomyopathy (TTC) have benign clinical course and prognosis, TTC can induce acute heart failure and hemodynamic instability. TTC mimics the clinical features of acute anterior wall myocardial infarction (AMI). Bedside clinicians often have a diagnostic dilemma when cardiac catheterization and angiography are either contraindicated or can cause potential ...

background: it is now well established that several environmental stress factors cause activation of p38 map kinase and jnk in various cell types to produce chemokines. objective: to investigate the expression of cxc chemokines gro/kc and sdf- 1a in rat's h4 hepatoma cells in response to heat shock, hyperosmolarity and oxidative stress. methods: hepatoma cells were maintained in mem medium...

Technology: Anti-inflammatory therapy for the treatment of septic shock Use: Sepsis or septic shock, which occurs when the host’s response to infection is excessive, is the fourth leading cause of long-stay intensive care admissions. Death may occur despite antimicrobial therapy if the host response to infection is either excessive or insufficient (Fig. 1); in fact, mortality has been reported ...

conclusions the early signs and symptoms of iscls may be subtle; therefore the diagnosis can easily be missed and prompt treatment of the syndrome may be postponed. thus, the clinician must consider iscls in differential diagnosis in cases of hypotension, hemoconcentration, and hypoalbuminemia. case presentation we present a 58-year-old female who presented with peripheral edema, leg pain, and ...

The incidence of cardiogenic shock in community studies has not decreased significantly over time. Despite decreasing mortality rates associated with increasing utilisation of revascularisation, shock remains the leading cause of death for patients hospitalised with acute myocardial infarction (MI). Although shock often develops early after MI onset, it is typically not diagnosed on hospital pr...

The quasi-static and dynamic compressive behavior of open-cell foams, textile cores, and pyramidal truss cores were investigated using a combination of experimental apparatus. Quasi-static tests were performed using a miniature loading stage and a Kolsky bar apparatus was used for intermediate deformation rates. For high deformation rates, a gas gun was employed. Optical observations of the sam...

Sepsis, along with the multiorgan failure that often accompanies the systemic inflammatory response syndrome (SIRS), is a leading cause of mortality in the intensive care unit. As many as 700,000 patients develop sepsis annually in the United States. Nearly half of these patients manifest severe sepsis and septic shock. The mortality for septic shock remains approximately 35% to 45%, despite a ...