AIM The aim of the study was to assess the efficacy of chemo-mechanical method for caries removal based on histological analysis and scanning electron microscopy of dentine samples. METHODS Forty-five freshly extracted human deciduous and permanent teeth with dentinal caries were used in this in vitro study. The teeth were allocated to two different technique groups. Chemo- mechanical caries ...

INTRODUCTION Dermatoglyphics is an extremely useful tool as a preliminary investigation method for diagnosing suspected genetic disorders. Caries being a multifactorial disease with the influence of genetic pattern, early identification of caries risk children with dermatoglyphics can help in using effective and efficient caries preventive measures. AIMS AND OBJECTIVES The study was undertake...

The purpose of this study was to provide a univariate and multivariate analysis of genomic microbial data and salivary mass-spectrometry proteomic profiles for dental caries outcomes. In order to determine potential useful biomarkers for dental caries, a multivariate classification analysis was employed to build predictive models capable of classifying microbial and salivary sample profiles wit...

BACKGROUND Dental caries is the most common microbial disease affecting mankind. Caries risk assessment methods, identification of biomarkers and vaccine development strategies are being emphasized to control the incidence of the largely preventable disease. Pattern recognition receptors such as the toll like receptors (TLR) have been implicated as modulators of host-microbial interactions. Sol...

Candida spp. are frequently detected in the mouths of children with extensive caries lesions compared with caries-free subjects. In this study we evaluated the presence of Candida spp. in association with mutans streptococci and lactobacilli in the saliva of children with dental decay, before and after anti-caries treatment. Samples of saliva from 14 children with caries lesions and from 13 car...

Using DNA subtractive hybridization, 49 unique gene segments were identified from a strain of Streptococcus mutans that was isolated from a patient with severe early childhood caries (S-ECC). Further hybridization with DNA from other S. mutans strains isolated from both caries-active and caries-free subjects yielded five unique sequences of DNA common to strains associated with S-ECC.

objectives: saliva plays an important role in prevention of dental caries. neutrophils are the first defense mechanism of the immune system. interleukins (ils) can regulate the activity of neutrophils. this study aimed to assess the neutrophil count and level of il-lβ and il-8 in the saliva of children with and without dental caries. materials and methods: this case-control study was performed ...

Mutans Streptococci, in particular S. mutans and S. sobrinus, are generally considered to be the prime etiological bacteria of human dental caries. The aim of this study was to determine the frequency of mutans streptococci in dental plaque in three groups of caries-free and caries-affected Venezuelan children aged 2-6, 7-12, 13-19 years, and their possible association with dental caries. The f...