BACKGROUND Endocytosis allows the import and distribution of cargo into a series of endosomes with distinct morphological and biochemical characteristics. Our current understanding of endocytic cargo trafficking is based on the kinetics of net cargo transport between endosomal compartments without considering individual endosomes. However, endosomes form a dynamic network of membranes undergoin...

The transit through a Border Check Point of cargo vehicles supposes, in the case Romanian highway network, carrying out process weighing and verifying transport licenses. limited number equipment long duration these processes cause large queues waiting times. A solution for problems is to use smart identify separate that require from exempted ones. separation made using external input data. qua...

The directional response and roll stability characteristics of a partly filled tractor semi-trailer vehicle, with cylindrical tank, are investigated in various maneuvers. The dynamic interaction of liquid cargo with the tractor semi-trailer vehicle is also evaluated by integrating a dynamic slosh model of the partly filled tank with five-degrees-of-freedom of a tractor semi-trailer tank mode...

In this study a hierarchical hub location problem with two layers is considered. The first layer includes small hubs and the second one includes a star-shaped network central hub. The considered case is a cargo delivery network where there is hierarchy between hubs. All the hubs and links are capacitated and there are three kinds of commodities for each of which there is a special kind of vehic...

Intracellular organelle transport is driven by motors that act upon microtubules or microfilaments. The microtubulebased motors, cytoplasmic dynein and kinesin, are believed to be responsible for retrograde and anterograde transport of intracellular cargo along microtubules. Many vesicles display bidirectional movement; however, the mechanism regulating directionality is unresolved. Directional...

Organized motions are hallmarks of living organisms. Such motions range from collective cell movements during development and muscle contractions at the macroscopic scale all the way down to cellular cargo (e.g., various biomolecules and organelles) transportation and mechanoforce sensing at more microscopic scales. Energy required for these biological motions is almost invariably provided by c...

Directional transport of specific cargos is tuned to specific molecular motors and specific cytoskeletal tracks. Myosin V transports its cargo on actin cables, whereas kinesin or dynein transport their cargo on microtubules. A recent study shows that an engineered kinesin can substitute for myosin V and its cargo-specific transport and subsequent cellular functions.

Overhead cranes are under-actuated systems. They have three outputs that need to be controlled, consisting of cargo swing angle, trolley displacement, and suspended cable length, but only two actuators: cargo lifting and trolley driving forces. The main objective of this study is to design a robust controller for an overhead crane that transfers cargo from point to point as fast as possible and...