To establish a comprehensive picture of the relationship between glutathione S-transferase omega 2 (GSTO2; MIM: 612314) gene N142D variant (rs. 156697) and breast cancer risk, the present meta-analysis was carried out. Studies published up to July 2012 with information about GSTO2 polymorphism and breast cancer risk were identified using several electronic databases. We identified 4 eligible st...

Background: The heterogeneous breast cancer is the most common cause of cancer-related mortality. Obesity defined by BMI is known as a major risk factor for breast cancer. Objective: The purpose of this study was to explore the role of obesity related-polymorphisms rs9939609 FTO and rs17782313 MC4R in breast cancer development. Materials and Methods: We obtained matched peripheral blood, serum ...

Background: Breast cancer is one of the most common diseases in women and causes more deaths rather than other cancers. The increasing trend of breast cancer in Iran makes clear the need of extensive breast cancer research in this area. Some studies showed that in the variety countries and even in the different areas in one country has different risk of breast cancer incidence and this is a rea...

abstract background: in iran gastric cancer is the second most common cancer and the most cause of death cancer, the aim of this study is provide map geographical distribution of gastric cancer and detect high risk cluster with use of space-time scan statistic. methods: this was an applied study. the data is provided from reports published by center for disease control office in ministry of hea...

Background: Venous thromboembolism (VTE) is a significant complication in cancer patients which was found in 4-20% of the patients. This study was aimed to evaluate risk factors of deep vein thrombosis (DVT) in cancer patients in an oncology center in Indonesia.  Methods: This was a retrospective cohort study. Data were obtained from medical records of adult cancer patients with DVT referring ...

background: in survival studies when the event times are dependent, performing of the analysis by using of methods based on independent assumption, leads to biased. in this paper, using copula function and considering the dependence structure between the event times, a parametric joint distribution has made fitting to the events, and the effective factors on each of these events would be determ...

bladder cancer is the most frequent genitourinary malignancy in iran. environmental and genetic factors are the two factors linked with bladder cancer expansion. the aim of this study was to investigate the role of pten gene and environmental risk factors on the progression and prognosis of bladder cancer.we evaluated 55 tumor specimens and 66 bladder mucosa samples of non-cancerous patients be...

background: human activities such as mining enhance the radioactivity levels above normal background which can lead to an incremental increase in the radiation risk to the population. materials and methods: 20 tailing enriched soil samples collected around maiganga coal mine, gombe, northeast nigeria were assessed for their 226ra, 232th and 40k contents using hpge gamma-ray detector. results: t...

AbstractBreast cancer is a multifactorial disease. Benign breast disease (BBD) is one of the most important risk factors for breast cancer. The etiology of BBD is unknown. It is divided into nonproliferative and proliferative diseases. The selection of studies will be based on titles, abstract screening, inclusion and exclusion criteria, and quality assessment. Previous studies have shown that ...

Background Endometrial cancer is a hormone-dependent disease and has been consistently associated with obesity. Non genetic lifestyle factors may account for more than 75% of endometrial cancer cases and represent potential targets for prevention of this disease. Insulin resistance induced by diet may play a particularly pernicious role in the development of endometrial cancer, possibly by redu...