Malignant tumors of head and neck carcinomas are the sixth most common type of cancer. Current systemic therapies for cancer show side effects in normal tissues and short-term efficacy due to drug resistance. Consequently, there is much interest in identifying new drugs for cancer treatment. Crocin (an active ingredient of saffron) has been shown to have cytotoxic effects on cancer cell lines. ...

salivary diagnostics has fascinated many researcheres and has been tested as a valuable tool in the diagnosis of many systemic conditions and for drug monitoring. advances in the field of molecular biology, salivary genomics and proteomics have led to the discovery of new molecular markers for oral cancer diagnosis, therapeutics and prognosis. oral cancer is a potentially fatal disease and the ...

recent investigations have been shown that inorganic nanomaterials including gold nanoparticles, nonporous and mesoporous silica nanoparticles, magneticnanoparticles, and quantum dots have shown great potential in bioimaging, targeted drug delivery, and cancer therapies. biocompatibility, ease of synthesis, and ease of surface functionalization are among the significant properties of nonporous ...

Based on the results of registration studies, drug cabozantinib, mechanism action which is determined by inhibition tyrosine kinases a relatively wide range cellular receptors, registered in treatment hepatocellular cancer, kidney cancer and thyroid cancer. This literature review collects data action, preclinical experiments phases I–III studies. Emphasis placed tolerability efficacy population...

malignant tumors of head and neck carcinomas are the sixth most common type of cancer. current systemic therapies for cancer show side effects in normal tissues and short-term efficacy due to drug resistance. consequently, there is much interest in identifying new drugs for cancer treatment. crocin (an active ingredient of saffron) has been shown to have cytotoxic effects on cancer cell lines. ...

Abstract Breast tumors generally consist of a diverse population cells with varying gene expression profiles. tumor heterogeneity is major factor contributing to drug resistance, recurrence, and metastasis after chemotherapy. Antibody-drug conjugates (ADCs) are emerging chemotherapeutic agents striking clinical success, including T-DM1 for HER2-positive breast cancer. However, these ADCs often ...