ANRIL (Antisense Noncoding RNA in the INK4 Locus), a long non-coding encoded human chromosome 9p21 region, is critical factor for regulating gene expression by interacting with multiple proteins and miRNAs. It has been found to play important roles various cellular processes, including cell cycle control proliferation. Dysregulation of associated several diseases like cancers cardiovascular dis...

Background: Fiber is a carbohydrate, which is neither completely digested nor absorbed in the small intestine, but may be fermented and plays a key role in the human health. We investigated the beneficial effects of fiber on major chronic diseases. Methods: It was extracted the relevant articles by searching the PubMed, ScienceDirect, and Scopus databases using the following keywords: dietary f...

background and objective: breast cancer is the commonest cancer of indian women. estrogen and progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...

Background: The average age of women with breast cancer in Iran is at least 10 years lower in comparison to developed countries and the incidence of the disease in Iranian women is on a rise. According to studies, diets that are diverse in food groups can play a role in protecting against chronic diseases including cardiovascular diseases and cancer. Diet diversity score is an indicator used to...

Background and Objective: Breast cancer is the commonest cancer of Indian women. Estrogen and Progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. Although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...

Saffron, the dried red-orange stigmas of Crocus sativus L, has been known as a flavoring agent, food coloring and traditional herbal medicine. Pharmacological effects of saffron are mainly attributed to crocin, crocetin, picrocrocin and safranal. These components especially crocin, have significant effects including antidepressant and anticonvulsant, analgesic, anti-cancer and other therapeutic...

for a long time, scientists have tried to describe disorders just by genetic or environmental factors. however, the role of epigenetics in human diseases has been considered from a half of century ago. in the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurod...

Everybody is born with the mammary gland. Mammary gland development occurs through various stages throughout embryonic, and stays dormant for males. Although it uncommon, male also gets breast cancer, occasionally. Male cancer accounts approximately 1% of all cases, increasing. When compared other rare diseases, understudied. Typically, treated in same way as female cancer. In this article, asp...