نتایج جستجو برای: caloric restriction igf 1 learning

تعداد نتایج: 3340349  

2013
Caitlin Mason Liren Xiao Catherine Duggan Ikuyo Imayama Karen E. Foster-Schubert Angela Kong Kristin L. Campbell Ching-Yun Wang Catherine M. Alfano George L. Blackburn Michael Pollack Anne McTiernan

High levels of insulin-like growth factor (IGF)-I may increase the risk of common cancers in humans. We hypothesized thatweight loss induced bydiet and/or exercisewould reduce IGF-I in postmenopausalwomen. Four hundred and thirty nine overweight or obese [bodymass index (BMI) 25 kg/m] women (50–75 years) were randomly assigned to: (i) exercise (N 1⁄4 117), (ii) dietary weight loss (N 1⁄4 118), ...

2010
James M. Isbell Robyn A. Tamboli Erik N. Hansen Jabbar Saliba Julia P. Dunn Sharon E. Phillips Pamela A. Marks-Shulman Naji N. Abumrad

OBJECTIVE Many of the metabolic benefits of Roux-en-Y gastric bypass (RYGB) occur before weight loss. In this study we investigated the influence of caloric restriction on the improvements in the metabolic responses that occur within the 1st week after RYGB. RESEARCH METHODS AND DESIGN: A mixed meal was administered to nine subjects before and after RYGB (average 4 +/- 0.5 days) and to nine mat...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2013
Caitlin Mason Liren Xiao Catherine Duggan Ikuyo Imayama Karen E Foster-Schubert Angela Kong Kristin L Campbell Ching-Yun Wang Catherine M Alfano George L Blackburn Michael Pollack Anne McTiernan

High levels of insulin-like growth factor (IGF)-I may increase the risk of common cancers in humans. We hypothesized that weight loss induced by diet and/or exercise would reduce IGF-I in postmenopausal women. Four hundred and thirty nine overweight or obese [body mass index (BMI) ≥ 25 kg/m(2)] women (50-75 years) were randomly assigned to: (i) exercise (N = 117), (ii) dietary weight loss (N = ...

Journal: :International journal of clinical and experimental medicine 2015
Wen Dong Rong Wang Li-Na Ma Bao-Lei Xu Jing-Shuang Zhang Zhi-Wei Zhao Yu-Lan Wang Xu Zhang

Recent studies indicated that different caloric intake may influence neuronal function. Excessive caloric intake associated with accelerated aging of the brain and increased the risk of neurodegenerative disorders. And low caloric intake (caloric restriction, CR) could delay aging, and protect the central nervous system from neurodegenerative disorders. The underlying mechanisms remain poorly u...

Journal: :Trends in Endocrinology & Metabolism 2009

Journal: :Aging cell 2007
Judith Campisi Paul Yaswen

Cancer is an age-related disease in organisms with renewable tissues. A malignant tumor arises in part from genomic damage, which can also drive age-related degeneration. However, cancer differs from many age-related degenerative diseases in that it entails gain-of-function changes that confer new (albeit aberrant) properties on cells, resulting in vigorous cell proliferation and survival. None...

2014
Fred Zülli Daniel Schmid

The concept of caloric restriction to retard signs of aging and to extend lifespan has gained a lot of interest in the past years. In our work we show for the first time caloric restriction-mimetic activity as a new anti-aging strategy in cosmetics. Up-regulation of Klotho expression and stimulation of AMPK activity was used to activate FOXO, the central cellular switch in the caloric restricti...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید