Road authorities considering the implementation of speed management interventions should have access to the results of scientifically robust evaluations on which to base their decisions. However, studies that evaluate a diverse range of interventions with comparable metrics are rare, with most focussing on one type, for example, types of signage, perceptual countermeasures or physical traffic c...

In a tractable model for cell invasion, the Caenorhabditis elegans anchor cell migrates through basement membranes towards a polarity cue provided by netrin. A new study reveals that the anchor cell polarity network can break symmetry and oscillate in the absence of netrin, suggesting the presence of interlinked positive and negative feedback loops, which are common in polarity pathways.

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(71) Applicants:Zainab JAGANI, Cambridge, MA (US); EPE" application No. 61/846,178, s s s Jul 15, 2013. Gregory HOFFMAN, Cambridge, MA ed. On Jul. 1, (US); Frank Peter STEGMEIER, Publication Classification Cambridge, MA (US); Craig Stephen MICKANIN, Cambridge, MA (US) (51) Int. Cl. CI2O I/68 (2006.01) (72) Inventors: Zainab JAGANI, Cambridge, MA (US); GOIN33/574 (2006.01) Gregory HOFFMAN, Cambr...

STUDY OBJECTIVE To assess the secondary health impacts of a traffic calming scheme on a community. METHODS Prospective cohort study of a randomly selected sample of the local community using postal questionnaires and pedestrian counts on the affected road six months before and six months after the implementation of the scheme. The setting was a community in which a traffic calming scheme was ...